SGS proderm GmbH
Schenefeld, Germany
NCT Number: NCT07096466
The objective of the study is to investigate the effect of one cosmetic product (exfoliator) containing Mitopure on the skin cell regeneration as well as on the skin hydration and skin barrier function in comparison to an untreated control area on the volar forearms.
Looking for future studies?
Notify Me18 year–65 year
All sexes
Interventional
Not applicable
Schenefeld, Germany
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
On day 1, the volar forearm test area will undergo DHA staining (250μl of 10% DHA solution applied under occlusion with Finn Chambers for 8 hours)
On day 1, the volar forearm test area will not undergo DHA staining.
The cosmetic product will be applied twice daily for two weeks to the volar forearm test area.
The cosmetic product will not be applied for two weeks to the volar forearm test area.
For two weeks on the face (excluding eye area), a cleansing cosmetic product containing Mitopure will be applied twice daily, and the cosmetic test product (that is used on forearms) will be applied once daily.
Time frame: 14 days
Skin cell regeneration is quantified by the change in skin colour. Skin colour is measured with the Chromameter instrument (skin colour unit of measure: Individual Typological Angle [ITA°]). Therefore, skin cell regeneration is measured by the change in ITA°, such that a larger positive change in ITA° represents improved skin cell regeneration. Skin cell regeneration will be calculated 4, 8, 11, and 14 days after baseline.
Time frame: 14 days
Change from baseline in skin hydration (assessed on skin capacitance by Corneometer) after 14 days.
Time frame: 14 days
Change from baseline in skin barrier function (assessed on Transepidermal water loss (TEWL) by Tewameter [g/(m²h)]) after 14 days.
Time frame: 14 days
Subjective evaluation of product traits assessed via questionnaire after 14 days. Product traits will be assessed by the subjects with a list of closed questions with the following predefined identical options to tick:-2 = Fully disagree; -1 = Rather disagree; 1 = Rather agree; 2 = Fully agree
Amazentis SA
Industry
CELL REGENERATION EFFICACY
Acronym: Exfoliator
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06956625
Healthy Skin
Schenefeld, Germany
View Trial DetailsNCT03625167
Healthy Skin
Berlin, Germany
View Trial DetailsNCT04406454
Healthy Skin, Neoplasms
Taipei, Beitou District, Taiwan
View Trial Details