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Completed

NCT Number: NCT04986878

Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty

Adductor canal block (ACB) has emerged as an option for postoperative regional analgesia in patients undergoing total knee arthroplasty (TKA).

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Key information

Conditions

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Aswan University Hospital, Aswān, Egypt

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About this study

Various approaches to the performance of peripheral nerve blocks for postoperative pain control in patients undergoing TKA have been described in the literature. These approaches include lumbar plexus block, femoral nerve block (FNB), with or without a sciatic nerve block, and most recently the ACB. FNB is a commonly used modality for postoperative analgesia after TKA. It is considered by some as the gold standard or the cornerstone of postoperative analgesia after TKA. However, FNB reduces quadriceps muscle strength essential for mobilization and active contribution in any physical rehabilitation program. Quadriceps weakness places the patients at risk of falling. which may be detrimental to postoperative recovery. The ACB has recently emerged as an appealing alternative to FNB as it is predominately a sensory nerve block of a more distal branch of the femoral nerve ( the saphenous nerve).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients scheduled for primary total knee arthroplasty with
  • American Society of Anesthesiologists (ASA) physical status I -III,
  • mentally competent and able to give consent for enrollment in the study.

Exclusion criteria

  • Patient younger than 18 years old or older than 70 years old
  • Allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone, and any of the drugs included in the multimodal perioperative pain protocol.
  • Revision surgeries were excluded.
  • Impaired kidney functions and patients with coagulopathy were also excluded.
  • Chronic pain syndromes and patients with chronic opioid use defined as the use of regular daily doses of systemic narcotics for the past 6 months prior to the surgery.
  • BMI of 40 or more
  • Pregnancy (positive urine pregnancy test result in Preop area on the morning of surgery)

Treatment and study plan

single-shot adductor canal block

Procedure

An ultrasound machine (Philips; Model: OTD020, AcBel Polytech Inc., Taiwan) with a 5-10 MHz linear probe was used to perform the adductor canal block immediately postoperatively.

Other names: Saphenous nerve block

Primary outcomes

  1. postoperative pain scores by visual analogue score

    Time frame: 48 hours

    visual analogue score is a straight, vertical 10-cm line with the bottom point representing "no pain" = (0cm) and the top point representing "the worst pain you could ever have" = (10 cm).

Secondary outcomes

  1. time to up and go test (minutes)

    Time frame: 48 hours

    determines how long it takes a person to get out of a chair

  2. six-minute walking test

    Time frame: 48 hours

    calculates the distance that can be walked in 6 minutes

  3. the 30-Second Chair test

    Time frame: 48 hours

    determines how many times a person can rise from a chair and sit down again in 30 seconds while keeping their arms crossed over their chest

Sponsors and collaborators

Lead sponsor

Aswan University Hospital

Other

Registry information

Official study title

Comparison Between the Analgesic Effects of Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Aug 3, 2021
Registry last updated
Aug 4, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.