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Completed

NCT Number: NCT02018783

Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment

The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste. One hundred and thirty-eight hypersensitive teeth were diagnosed and randomized into four groups according to the therapeutic agent of each desensitizing cream tested: 1) strontium acetate and calcium carbonate, 2) calcium carbonate and arginine 8%, 3) calcium phosphate nanoparticles and 4) a control toothpaste. The desensitizing creams were applied according to the manufacturer's instructions. Cervical dentin hypersensitivity was assessed at baseline, immediately, 24 hours and 30 days after the treatment. Cold and evaporative tests were used to assess the sensitivity level.

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Key information

Conditions

Dentine Hypersensitivity Dentin Sensitivity Stomatognathic Diseases Tooth Diseases

Age range

22 year–48 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Periodontics Clinic, Department of Dentistry

Diamantina, Minas Gerais, 39100000, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • subjects 18 years or older
  • in good general and oral health; have complaint of CDH in teeth distributed in all 4 quadrants
  • not making use of desensitizing agents
  • not having undergone periodontal treatment over the past 3 months
  • respond to evaporative stimulus with a score ≥ 1.5 cm on VAS

Exclusion criteria

  • patients who presented restorations and caries near the exposed dentin of the hypersensitive teeth
  • who made frequent use of painkillers, anti-inflammatory and antidepressants drugs

Treatment and study plan

Colgate

Procedure

Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure

Sensodyne

Procedure

Digital application for 60 seconds.

Nano P

Procedure

Slow-speed handpiece with a Robson brush for 10 seconds

Cocorico

Procedure

Digital application for 60 seconds

Primary outcomes

  1. cervical dentin hypersensitivity

    Time frame: 30 days

    The cervical dentin hypersensitivity was evaluated by an air blast (evaporative stimulus) for 5 seconds, and by a tetrafluoroethane spray (cold stimulus) for 5 seconds.

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Registry information

Official study title

Clinical Evaluation of the Effectiveness of Immediate Relief Obtained With Desensitizing Creams - A Controlled, Randomized, Triple Masked, Split-Mouth Clinical Trial

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Dec 23, 2013
Registry last updated
Dec 23, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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