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NCT Number: NCT07660770

Simulation Training for Adolescent Leukemia Care in Nursing Students

This study aims to evaluate the effects of scenario-based simulation training for adolescent leukemia care on nursing students' perceived stress, knowledge level, and learning satisfaction. Nursing students often encounter challenges when managing complex clinical situations involving pediatric oncology patients. Simulation-based education may help students develop clinical skills and confidence in a safe learning environment.

The study investigates whether participation in an adolescent leukemia simulation scenario improves students' knowledge related to extravasation management, affects their perceived stress levels, and enhances their learning satisfaction. In addition, students' experiences and perceptions regarding the simulation training will be explored through qualitative interviews.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Nursing Education Behavior Behavioral Symptoms Hematologic Diseases Hemic and Lymphatic Diseases Leukemia Neoplasms Neoplasms by Histologic Type Simulation Training Stress, Psychological

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Atılım University, Faculty of Health Sciences, Department of Nursing

Ankara, 06830, Turkey (Türkiye)

About this study

Simulation-based education is increasingly used in nursing programs to bridge the gap between theoretical knowledge and clinical practice. Pediatric oncology care requires specialized knowledge and clinical decision-making skills, particularly in managing complications such as chemotherapy extravasation. However, nursing students often have limited opportunities to encounter such situations during clinical placements.

This mixed-methods study will evaluate the effectiveness of an adolescent leukemia scenario-based simulation training program among third-year nursing students. The quantitative component will employ a single-group pretest-posttest quasi-experimental design. Participants will complete baseline assessments before the simulation intervention and follow-up assessments immediately after the simulation and debriefing sessions.

The simulation scenario focuses on the recognition and management of chemotherapy extravasation in an adolescent patient with leukemia. The intervention will be conducted in a simulation laboratory using a structured process including prebriefing, simulation implementation, and debriefing based on the Promoting Excellence and Reflective Learning in Simulation (PEARLS) framework.

Quantitative outcomes will include perceived stress, knowledge regarding extravasation management, and learning satisfaction. Qualitative data will be collected through semi-structured focus group interviews conducted after the simulation experience. The qualitative findings will provide a deeper understanding of participants' experiences, perceptions, clinical reasoning processes, and learning outcomes.

Data will be analyzed using appropriate descriptive and inferential statistical methods for the quantitative component and thematic analysis for the qualitative component. Findings from both components will be integrated to provide a comprehensive evaluation of the educational effectiveness of adolescent leukemia scenario-based simulation training in undergraduate nursing education.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Third-year nursing students enrolled at Atılım University, Faculty of Health Sciences, Department of Nursing
  • Voluntary participation in the study
  • Not having previously taken the NURS302 - Child Health and Diseases course

Exclusion criteria

  • Withdrawal from the study at any stage
  • Incomplete completion of data collection forms

Treatment and study plan

Scenario-Based Simulation Training

Other

A simulation-based educational intervention consisting of prebriefing (3 min), environmental orientation (3 min), scenario-based simulation on extravasation management in an adolescent leukemia patient (10 min), and structured debriefing using the PEARLS model (30 min). Pre- and post-tests were administered to assess perceived stress, knowledge level, and student satisfaction.

Other names: Simulation-Based Learning

Primary outcomes

  1. Extravasation Knowledge Level

    Time frame: Baseline (pre-simulation) and immediately after simulation and debriefing (post-simulation, approximately 1 hour later)

    Change in nursing students' knowledge about extravasation management, assessed using a 10-item multiple-choice knowledge test developed by the researchers. Each correct answer scores 1 point (total: 0-10). Higher scores indicate better knowledge.

  2. Perceived Stress Level

    Time frame: Baseline (pre-simulation) and immediately after simulation and debriefing (post-simulation, approximately 1 hour later)

    Change in perceived stress measured with the Nursing Student Perceived Stress Scale (NSPSS; Karaca et al., 2015), a 29-item, 5-point Likert scale with 6 subscales. Total scores range from 0 to 116; higher scores indicate greater perceived stress.

Secondary outcomes

  1. Student Satisfaction and Self-Confidence in Learning

    Time frame: Immediately after simulation and debriefing (post-simulation only, approximately 1 hour after baseline)

    Student satisfaction assessed using the Student Satisfaction and Self-Confidence in Learning Scale (NLN; Turkish adaptation by Karaçay & Kaya, 2017), a 13-item, 5-point Likert scale with 2 subscales. Scores range from 13 to 65; higher scores indicate greater satisfaction and self-confidence.

Other outcomes

  1. Students' Simulation Experiences (Qualitative)

    Time frame: Immediately after debriefing session (approximately 1-1.5 hours after baseline)

    Themes derived from semi-structured focus group interviews conducted after simulation, exploring students' experiences regarding stress, clinical decision-making, teamwork, and learning processes. Analyzed using thematic analysis with MAXQDA.

Sponsors and collaborators

Lead sponsor

Atılım University

Other

Registry information

Official study title

The Effect of Scenario-Based Simulation Training for Adolescent Leukemia Care on Nursing Students' Perceived Stress, Knowledge, and Learning Satisfaction: A Mixed-Methods Study

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 22, 2026
Registry last updated
Jun 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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