Skip to main content
OpenTrials
Completed

NCT Number: NCT06998030

Silent Threat: Impact of Preoperative Albumin Levels on Outcomes in Geriatric Cancer Surgery

This retrospective, single-center study aims to evaluate the impact of preoperative albumin levels on postoperative outcomes in geriatric patients (aged 65 and above) undergoing cancer surgery. The study will compare postoperative complication rates, length of hospital stay, and intensive care needs between patients with hypoalbuminemia and those with normal albumin levels.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Neoplasms Aged Blood Protein Disorders Hematologic Diseases Hemic and Lymphatic Diseases Hypoalbuminemia Hypoproteinemia Malnutrition Nutrition Disorders Nutritional and Metabolic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Reanimation

Ankara, Yenimahalle, 06200, Turkey (Türkiye)

About this study

Malnutrition is a significant risk factor for postoperative complications in elderly cancer patients. Preoperative serum albumin is a key biomarker reflecting nutritional and inflammatory status. This study will retrospectively review the medical records of 330 geriatric patients (≥65 years) who underwent cancer surgery at Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. Patients will be grouped according to preoperative albumin levels: Group 1 (<3.5 g/dL, hypoalbuminemia) and Group 2 (≥3.5 g/dL, normal). The primary aim is to compare postoperative complication rates, length of hospital stay, and intensive care requirements between these groups. The findings are expected to clarify the prognostic value of albumin and support individualized perioperative management in geriatric cancer surgery.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 65 years or older
  • Diagnosed with cancer and underwent cancer surgery
  • Preoperative albumin level recorded before surgery

Exclusion criteria

  • Preoperative sepsis, severe infection, or active inflammatory disease
  • Emergency or palliative surgery
  • Missing preoperative albumin value
  • Incomplete medical records or follow-up data

Treatment and study plan

Primary outcomes

  1. Postoperative Complication Rate

    Time frame: within 30 days after surgery

    The proportion of patients experiencing any postoperative complication (including but not limited to pulmonary complications, infections, or other adverse events) within 30 days after surgery, as assessed by clinical records and standardized criteria (e.g., Clavien-Dindo classification)

Secondary outcomes

  1. Length of Hospital Stay

    Time frame: postoperative first 30 days

    Total number of days from the date of surgery to hospital discharge.

  2. Postoperative Intensive Care Unit (ICU) Admission

    Time frame: immediately after the surgery

    The proportion of patients requiring ICU admission after surgery

  3. Length of ICU Stay

    Time frame: 30 days after surgery

    The total duration of ICU stay following surgery

  4. 30-day Postoperative Mortality

    Time frame: within 30 days after surgery

    All-cause mortality within 30 days after surgery

  5. Incidence of Specific Postoperative Pulmonary Complications

    Time frame: 30 days after surgery

    The number of patients developing pulmonary complications (e.g., pneumonia, pleural effusion, atelectasis, ARDS, respiratory failure) within 30 days after surgery

Sponsors and collaborators

Lead sponsor

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Other

Registry information

Official study title

Silent Threat: How Do Preoperative Albumin Levels Affect Outcomes in Geriatric Cancer Surgery

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 31, 2025
Registry last updated
Apr 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.