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OpenTrials
Completed

NCT Number: NCT05420298

Short Term Effect of Cervical Mobilization vs Manipulation on Blood Pressure in Hypertensive Subjects

Spinal pain or misalignment is a very common disorder affecting a significant number of populations resulting in substantial disability and economic burden. Various manual therapeutic techniques such as spinal manipulations and mobilizations can be used to treat and manage pain and movement dysfunctions such as spinal malalignments and associated complications. These manual therapeutic techniques can affect the cardiovascular parameters .

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

27 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Cairo, 11432, Egypt

About this study

Group A group (n=20). All participants will receive only single session of neck mobilization. Grade IV unilateral posteroanterior pressure and sustained extension to be applied restricted joints and muscle energy technique.

  • Group B (n=20) will receive single session of neck manipulation with high-velocity, low-amplitude thrust over restricted joints (one at a time) with the goal of restoring normal range of motion in the joint.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • SBP ranging from 135 to 159 mm Hg or DBP ranging from 85 to 99 mm Hg over 3 qualifying BP screening visits
  • The age of participants will range from 27 to 60 years old.
  • Body mass index of participants will range between < 39 kg/m².

Exclusion criteria

  • cardiovascular diseases or surgery, including second- or third-degree heart block, angina pectoris, defibrillator, valvular disease, recent myocardial infarction, cardiac surgery in the past 12 months.
  • history of stroke.
  • body mass index (BMI) greater than 39 kg/m2.
  • pregnancy.

Treatment and study plan

cervical mobilization

Other

All participants will receive only single session of cervical mobilization

Cervical Manipulation

Other

All participants will receive only single session of cervical manipulation

Primary outcomes

  1. systolic blood pressure measurement

    Time frame: it will be measured immediately before and after single session treatment

    systolic pressure - the pressure when your heart pushes blood out and is measured by Mercury sphygmomanometer and stethoscope

Secondary outcomes

  1. diastolic blood pressure

    Time frame: it will be measured immediately before and after single session treatment

    the pressure when your heart rests between beats is measured by Mercury sphygmomanometer and stethoscope

  2. oxygen saturation

    Time frame: it will be measured immediately before and after single session treatment

    Oxygen saturation is a vital parameter to define blood oxygen content and oxygen delivery and is measured by pulse oximetry

  3. perfusion index

    Time frame: it will be measured immediately before and after single session treatment

    Perfusion index is an indication of the pulse strength at the sensor site. The PI's values range from 0.02% for very weak pulse to 20% for extremely strong pulse.Perfusion index is normally monitored with pulse oximeters

  4. pain assessment

    Time frame: it will be measured immediately before and after single session treatment

    The visual analog scale (VAS) is a tool widely used to measure pain

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Short Term Effect of Cervical Mobilization vs Manipulation on Blood Pressure in Hypertensive Subjects( Randomized Control Trial)

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jun 15, 2022
Registry last updated
Jul 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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