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OpenTrials
Completed

NCT Number: NCT05783752

Short, Simple, Exercise to Improve Circadian Dependent Postprandial Glycemic Responses

The goal of this clinical trial is to test whether one minute of stair stepping at a comfortable pace can reduce blood sugar after meals. The main objectives of the study are:

Compare continuously measured post-meal glucose after stair-stepping to control condition Compare continuously measured post-meal glucose after stair-stepping between meals Assess interaction between condition and meal to determine if the effect of stair-stepping on post-meal glucose depends on meal

Participants will be in the study for 10 days and will be asked to:

Wear a continuous glucose monitor over the course of the study Perform either one minute of comfortable pace stair stepping 15 min after each meal OR no exercise 1 hour after eating a meal on alternating days Perform a dietary recall every two days Perform no exercise within one hour after each meal on any day during the study Consume no calories within one hour after each meal during the study

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Key information

Conditions

Postprandial Glycemic Response Glucose Metabolism Disorders Hyperglycemia Metabolic Diseases Nutritional and Metabolic Diseases Postprandial Hyperglycemia Postprandial Insulin

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

San Diego State University

San Diego, California, 92182, United States

About this study

After being informed about the study and potential risks, all participants giving written informed consent will undergo a screening to determine eligibility for study entry. At day 1, patients who meet the eligibility requirements will be randomly assigned to Arm 1(stair stepping day followed by no exercise day sequence) or Arm 2(no exercise day followed by stair stepping day sequence). At this time participants will also be familiarized with the continuous glucose (i.e., blood sugar) monitor they will wear for ten days, be instructed how to fill out a food log every day and determine a comfortable stair stepping pace. On day 10 participants will return to the lab for sensor removal and transmitter return.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • between 18 and 65 years
  • able to climb and descend stairs
  • access to stairs

Exclusion criteria

  • glycemic medications that vary in dosage
  • dosage from meal to meal or day to day (eg insulin titrated to meal size or carbohydrate content)

Treatment and study plan

Stair stepping

Behavioral

1 minute of stair-stepping (30 seconds up, 30 seconds down) at a self-selected pace identified on day 0 starting 15 minutes after each meal

No Exercise Control

Behavioral

Participants avoid exercise within 1 hour of eating a meal

Primary outcomes

  1. Postprandial Blood Glucose

    Time frame: continuous measure from meal consumption up to 1 hour post meal

    mg/dL

Sponsors and collaborators

Lead sponsor

San Diego State University

Other

Registry information

Official study title

Effects of Stair Stepping on Late Day Postprandial Glycemia

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Mar 24, 2023
Registry last updated
Jul 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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