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NCT Number: NCT06454253

Short- and Long-term Outcomes of Robotic vs Laparoscopic Right Colon Cancer: a 10-year Single-center Retrospective Study

The goal of this observational study is to evaluate the short-term outcomes and long-term outcomes of robot-assisted right colon group for cancer compared to laparoscopic-assisted right colon group. This is a large sample study based on ten years of clinical data. The main question it aims to answer is: What are the advantages of da Vinci robot right hemicolectomy compared to laparoscopic right hemicolectomy, and is there a difference in long-term efficacy between the two methods.

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Key information

About this study

Colorectal cancer (CRC) is highly prevalent worldwide. In China, CRC ranks high among the population of men and women with cancer. The incidence and mortality rates of CRC are rising quickly in developing countries, and it is the fourth most deadly cancer in the world. In particular, the right colon cancer (RCC) is continuously growing in China, and the early symptoms of RCC are not typical. one of the most useful ways for RCC is surgical is a surgical operation. Along with the development of minimally invasive surgery, the use of laparoscopy for colon cancer is widely accepted and has become one symbolic surgical technology. Studies have demonstrated that laparoscopic colonic surgery is related to reduced pain after operation, shorter rehabilitation time, shorter length of hospital stay, reduced the time of ileus after surgery, and reduced surgical site infection.

Nevertheless, laparoscopic surgery also has its shortcoming, including a limited range of motion, slow learning and growth, and physiological tremor cannot be eliminated.The emergence of robots has broken the inherent disadvantage of laparoscopy. It has achieved similar or better results in previous studies. Based on these advantages, robotic surgery has received much attention from the surgeons. With the first robotic surgery in the field of colon cancer was reported in 2002, there are some studies proved the safety and feasibility by using robot,However, most studies with small sample sizes and with cases at a relatively early stage.

Therefore, the purpose of this study is to compare the short-term and long-term outcomes between RARC and LARC in the treatment of right colon cancer in our center.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The age is more than 18 years old and less than or equal to 85 years old
  • No distant metastasis (including pelvic cavity, peritoneum, liver, lung, brain, bone, distant lymph node metastasis, etc.) is judged by ultrasound, CT, PET-CT, etc
  • Preoperative colonoscopy showing that the tumor was located in the ileocecal region, ascending colon, hepatic flexure, or transverse colon with pathology showing malignancy
  • signed informed consent. -

Exclusion criteria

  • multiple primary colorectal cancer
  • recurrent right colon cancer
  • preoperative neoadjuvant chemotherapy
  • emergency surgery for intestinal obstruction, bleeding or perforation
  • incomplete data and missing follow-up data. -

Treatment and study plan

Da Vinci Robot Surgical System

Device

Performing surgery on right colon cancer patients using the da Vinci robotic surgical system or laparoscopic surgical system

Other names: Laparoscopic surgical system

Primary outcomes

  1. overall survival

    Time frame: 5 years after surgery

    months

  2. disease-free survival

    Time frame: 5 years after surgery

    months

Secondary outcomes

  1. the rate of postoperative complications

    Time frame: 1 months after surgery

    rate

  2. operative time

    Time frame: Intraoperative

    minutes

  3. estimation of blood loss

    Time frame: Intraoperative

    milliliters

  4. number of retrieved lymph nodes

    Time frame: Intraoperative

    numbers

  5. days after postoperative hospital stay

    Time frame: 1 months after surgery

    days

  6. time to first exhaust

    Time frame: 1 weeks after surgery

    hours

  7. time to liquid diet

    Time frame: 1 weeks after surgery

    hours

  8. the rate of intracorporeal anastomosis

    Time frame: 1 months after surgery

    rate

Sponsors and collaborators

Lead sponsor

Taiyuan Li

Other

Registry information

Official study title

the Ethics Committee of the First Affiliated Hospital of Nanchang University

Important dates

Study start
2014
Primary completion
2024
Study completion
2024
First posted
Jun 12, 2024
Registry last updated
Jun 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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