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Completed

NCT Number: NCT05906667

Sharing History Through Active Reminiscence and Photo-imagery - With MCI

The SHARP-MCI study tests impact of walking and social reminiscence on cognitive function, blood pressure, and weight among healthy Black Americans and those experiencing mild cognitive impairment (MCI).

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Key information

Conditions

Age range

55 year–95 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Oregon Health & Science University

Portland, Oregon, 97239, United States

About this study

For 6 months (24 weeks), triads of healthy and MCI Black adults aged 55 and over walk 3x/week (1 mile) in Portland's historically Black neighborhoods. Triads follow GPS-mapped routes accessible via the SHARP walking application on a group tablet device. At three points along each route, GPS-triggered "Memory Markers" (historical images of local Black culture and life from1940-2010) appear on the tablet screen serving as a conversational reminisce prompt as the triad walks. At baseline and 24 weeks, cognitive function is measured via the Montreal Cognitive Assessment (MoCA), and weight and blood pressure are measured. Pre-post health surveys rate activity levels, days feeling downhearted/blue, energy level, and health status. Program evaluation surveys at month 1, 3, 6 assess mood, pace and dose of walking, prompt effectiveness, program readiness, and liklihood to recommend program to others. Focus groups at month 1, 3, 6 evaluate participants' program experience and needed changes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Self-identified African American
  • > 55 years old
  • Reside or resided for >10 years in Portland's historically Black neighborhoods (to be familiar with Memory Markers about this area)
  • Able to ambulate independently. Participants (n=7) with MCI will meet criteria consistent with those defined by Jak et al. 2009 and with criteria outlined by the NIA-Alzheimer's Association workgroup (2011)
  • Participants without cognitive impairment (n=14) will have an MMSE score > 24 (and not meet MCI criteria).
  • Participants' cognitive function should allow them to get to/ from walk locations independently or with minimal assistance

Exclusion criteria

  • Serious or unstable medical condition (such as, but not limited to, cardiovascular disease, pulmonary disease, or severe arthritis) where participation in the trial would, in the opinion of the investigator, pose a significant health risk to the subject.
  • Diagnosis of Alzheimer's disease, vascular dementia, Parkinson's disease, or other dementing illness.

Treatment and study plan

Sharing History through Active Reminiscence and Photo-imagery (SHARP)

Behavioral

Participants engage in neighborhood walks and conversational reminisce three times per week over 24 weeks

Other names: SHARP

Primary outcomes

  1. Cognitive function

    Time frame: 24 weeks

    Pre/post Montreal Cognitive Assessment

Secondary outcomes

  1. Blood pressure

    Time frame: 24 weeks

    pre/post blood pressure reading

  2. Weight

    Time frame: 24 weeks

    pre/post weight measurement

Sponsors and collaborators

Lead sponsor

Oregon Health and Science University

Other

Registry information

Official study title

Sharing History Through Active Reminiscence and Photo-imagery: A Neighborhood Approach to Increase Physical Activity and Social Engagement

Acronym: SHARP-MCI

Important dates

Study start
2017
Primary completion
2018
Study completion
2020
First posted
Jun 18, 2023
Registry last updated
Jun 18, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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