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OpenTrials
Completed

NCT Number: NCT06840847

Sexual Coercion in Breast Cancer Patients Treated With Luteinizing Hormone-Releasing Hormone Agonists (LHRHa )

The use of luteinizing hormone-releasing hormone agonists(LHRHa) to suppress ovarian function is a common strategy for treating premenopausal, hormone receptor-positive breast cancer. However, this approach can lead to more severe and prolonged menopausal symptoms, which can further impact intimate relationships and sexual function. Sexual coercion, encompassing both overt and subtle forms of pressure, is a significant global public health concern that threatens individual well-being.

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Key information

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Kastamonu University

Kastamonu, Merkez, 37150, Turkey (Türkiye)

About this study

Objective: The use of luteinizing hormone-releasing hormone agonists(LHRHa) to suppress ovarian function is a common strategy for treating premenopausal, hormone receptor-positive breast cancer. However, this approach can lead to more severe and prolonged menopausal symptoms, which can further impact intimate relationships and sexual function. Sexual coercion, encompassing both overt and subtle forms of pressure, is a significant global public health concern that threatens individual well-being.

Methods: This study is a randomized controlled study. In this study, the validated Turkish version of the Sexual Coercion in Intimate Relationship Scale was utilized to investigate whether patients receiving LHRHa therapy experienced higher rates of sexual sexual coercion compared to those taking tamoxifen. The study included 40 patients using LHRHa and 39 patients using tamoxifen. The instrument assessed partner sexual coercion across three subdomains: resource manipulation/sexual coercion, commitment manipulation, and defection threat.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • being over 18 years of age
  • willingness to participate in this study
  • having received treatment for breast cancer
  • having a history of breast cancer surgery
  • having an active relationship with a spouse or partner.

Exclusion criteria

  • having any neuropsychiatric disorder
  • having any mental illness
  • having a history of gynecological surgery
  • currently receiving active chemotherapy or less than 3 months since completing chemotherapy
  • receiving treatment for metastatic disease
  • The use of selective serotonin reuptake inhibitors

Treatment and study plan

Sexual Coercion

Behavioral

This study aimed to investigate whether patients receiving LHRHa treatment experienced sexual coercion at a higher rate than those using tamoxifen. 40 patients using LHRHa and 39 patients using tamoxifen were included in the study.

Primary outcomes

  1. LHRHa

    Time frame: for 10 months

    It was examined whether patients receiving LHRHa treatment were exposed to sexual pressure.

  2. Tamoxifen

    Time frame: for 10 months

    It was examined whether patients receiving tamoxifen treatment were exposed to sexual pressure.

Sponsors and collaborators

Lead sponsor

Canan Kas

Other

Registry information

Acronym: LHRHa

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Feb 21, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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