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OpenTrials
Completed

NCT Number: NCT00677651

Sex Differences in Gene Expression in Human Adipose Tissue

This project was created to assess sex differences in adipose tissue gene expression in different locations in the body. The primary objectives are to understand:

1. The mechanisms of differential body fat distribution in men and women 2. How body fat distribution is affected by reproductive hormones 3. The mechanisms linking fat distribution to health risks such as diabetes

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Key information

Conditions

Healthy Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–35 year

Sex eligibility

All sexes

Study type

Observational

Primary location

UCSD

La Jolla, California, 91963-0063, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Caucasian men and women 20-35 years of age
  • Lean (BMI less than 25)
  • Obese (BMI 30-35)

Exclusion criteria

  • Hormonal birth control
  • Pregnancy
  • Smokers
  • History of diabetes, kidney, liver or thyroid disease
  • History of cancer

Treatment and study plan

Adipose Biopsy

Procedure

Adipose tissue will be sampled from the abdomen and buttock

Blood sample

Procedure

Blood will be sampled from an IV line

CT Scan

Radiation

Single image at the level of the liver

DEXA

Radiation

Whole body scan

Primary outcomes

  1. Adipose and blood sampling

    Time frame: 1 year

Secondary outcomes

  1. CT scan and DEXA scan

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

University of California, San Diego

Other

Collaborators

  • University of Maryland

Registry information

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
May 14, 2008
Registry last updated
Aug 18, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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