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NCT Number: NCT06455800

Severe Lung Disease in Childhood

Only little information exists about the long term consequences of having severe lung disease in childhood. The patient population is heterogenous and the prognostic markers are few.

This observational study will investigate which parameters that can be used to predict the outcome of having severe lung disease in childhood.

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Key information

Conditions

Lung Disease Chronic

Age range

1 day–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hans Christian Andersen Children's Hospital

Odense, 5000, Denmark

Location status: Recruiting

Location contact

Josefine Gradman, PhD

CONTACT

[email protected]

0045 29241375

About this study

All patients aged 0-18 years at the HCA Childrens Hospital with a severe lung disease will prospectively be registered in a database.

At a yearly follow up, data from the patient record will be registered. Informed consent from the patients and/or their parents will be obtained. Registered data will include height, weight, results of lung function tests and imaging diagnostics.

The study will provide knowledge of the prognosis of different lung diseases and how to monitor lung function in children.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

severe lung disease -

Exclusion criteria

no informed consent

-

Treatment and study plan

lung function measurements

Diagnostic Test

Patients will once a year be monitored with different lung function methods

Primary outcomes

  1. FEV1

    Time frame: 18 years

    liter

  2. FVC

    Time frame: 18 years

    liter

  3. Lung Clearance Index (LCI)

    Time frame: 18 years

    number

Secondary outcomes

  1. height

    Time frame: 18 years

    meters

Study contacts

Contact information is provided by the study sponsor or research team.

Josefine Gradman, PhD

CONTACT

[email protected]

0045 29241375

Sponsors and collaborators

Lead sponsor

Odense University Hospital

Other

Registry information

Official study title

Long Term Outcome of Severe Lung Disease in Childhood

Important dates

Study start
2024
Primary completion
2039
Study completion
2039
First posted
Jun 12, 2024
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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