Serum MIF in Acute Kidney Injury

Acute kidney injury (AKI) is a common complication in critical care patients. Currently no parameters are available for early prognosis of AKI. Macrophage migration inhibitory factor (MIF) has been associated with AKI in clinical studies. The aim of this study is to evaluate the time course of MIF concentrations in patients with AKI.

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Key information

Conditions

Acute Kidney Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Medical University of Vienna

Vienna, 1090, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Exclusion criteria

Age < 18 years and > 80 years
Patients with chronic dialysis
Patients with continuous hemodialysis, hemofiltration or hemodiafiltration within 4 weeks prior to the study
Patients with an expected length of ICU stay shorter than 3 days
Patients with a low probability of surviving the first 2 days after ICU admission
Pregnancy and nursing

Treatment and study plan

Blood draw for measurement of MIF

Other

Observational study, no intervention

Primary outcomes

Macrophage migration inhibitory factor

Time frame: Up to 14 days

Secondary outcomes

Serum creatinine

Time frame: Up to 14 days

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Official study title

Macrophage Migration Inhibitory Factor in the Serum of Critically Ill Patients as an Early Marker for Acute Kidney Injury

Important dates

Study start: 2015
Primary completion: 2019
Study completion: 2023
First posted: Feb 2, 2015
Registry last updated: Mar 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed