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OpenTrials
Completed

NCT Number: NCT03325036

Serum Immunological Profiles in Head and Neck Cancer Patients Receiving Curative Radiotherapy

The purpose of the study is to investigate the clinical usefulness of serum levels of immunologic profiles including pro/anti-inflammatory interleukins, other detectable serum biomarkers including transforming growth factor b1 (TGFb1) or soluble major histocompatibility complex Class I chain-related peptide A (sMICA), and leukocyte subpopulations in head and neck cancers patients receiving curative radiotherapy, as prognostic biomarkers for disease recurrence and survival.

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Key information

Conditions

Head and Neck Cancers Patients

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

National Taiwan University Hospital

Taipei, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with head and neck cancer receiving curative radiotherapy in NTUH radiation therapy department.

Exclusion criteria

  • Patients with head and neck cancer NOT receiving curative radiotherapy in NTUH radiation therapy department.

Treatment and study plan

Serum levels of immunologic profiles

Diagnostic Test

Serum levels of immunologic profiles before and after chemoradiotherapy

Primary outcomes

  1. Disease progression

    Time frame: Three years

    Tumor local recurrence or distant metastasis

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

Serum Immunological Profiles in Head and Neck Cancer Patients Receiving Curative Radiotherapy: Quantitative Analysis and Prognostic Implication

Important dates

Study start
2017
Primary completion
2024
Study completion
2024
First posted
Oct 30, 2017
Registry last updated
Dec 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.