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NCT Number: NCT06748365

Serum Ferritin and Prognosis of DKA

the aim of this study is to: evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA. Specifically, the correlation between its level and the severity of DKA at presentation and determine its prognostic value in predicting short-term outcomes.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag university Hospitals

Sohag, Sohag Governorate, 82524, Egypt

Location status: Recruiting

About this study

Ferritin studies and correlation to acute events like stroke or Mi was done before, however some studies have found a correlation with the degree and prognosis of these diseases and others not. However no study was tried on DKA patients before so the investigators are trying to find if Ferritin would have a relation with patients of Dka and could be used as a prognostic tool (for example we found in this study when level is less than "200" patients mostly has good prognosis) this is just an example or (serrum ferritin turned out to be irrelevant to DKA prognosis as patients would have good prognosis despite number value) and this will be in selected patients according to criteria to exclude any chronic condition in the investigators hospital care units.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-

All patients with DKA :

  • Adult Aged 18 years old or older .
  • Type 1 DM , type 2 DM
  • Diagnosis of DKA based on the American Diabetes Association criteria: blood glucose >250 mg/dL, arterial pH <7.3, serum bicarbonate <18 mEq/L,

Exclusion criteria

  • Patients age less than 18 years old
  • Iron deficiency anemia and iron overload
  • Chronic Inflammatory Diseases: Conditions such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease
  • Acute and chronic infections, including bacterial, viral, and fungal infections
  • Pt presented with other acute complication (MI,stroke)
  • CKD patients
  • Patients with chronic liver diseases
  • Patients with malignancy
  • Pregnant women.

Treatment and study plan

Primary outcomes

  1. evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA. Specifically, the correlation between its level and the severity of DKA at presentation and determine its prognostic value

    Time frame: Through the study completion, an average of 1 year

Study contacts

Contact information is provided by the study sponsor or research team.

Joseph Medhat Sobhy, resident in internal medicine

CONTACT

[email protected]

+2001011041077

Marium Medhat Sobhy, resident in opthalmology

CONTACT

[email protected]

+2001023322977

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Role of Ferritin in the Clinical Presentation and Short-Term Prognosis of Diabetic Ketoacidosis

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 27, 2024
Registry last updated
May 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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