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OpenTrials
Completed

NCT Number: NCT03964428

Serum Ferritin and Hepicidin Concentration in Chronic Periodontitis Patients With T2DM

serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease

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Key information

Conditions

Periodontitis Diabetes Mellitus Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Mouth Diseases Nutritional and Metabolic Diseases Periodontal Diseases Stomatognathic Diseases Type2 Diabetes

Age range

30 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Nayroz Abelfattah Tarrad

Cairo, Egypt

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm with T2DM
  • systemically healthy patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm
  • healthy subjects had clinically healthy gingiva with ≤ 3mm pocket probing depth (PPD), nearly zero plaque index (PI), gingival index (GI), zero CAL.

Exclusion criteria

  • (I) Pregnancy or lactation, (II) History of receiving professional periodontal treatment during the past 6 months; (III) Treatment with any type of medications and/ or antibiotics during the past 3 months and (IV) Current or former smokers.

Treatment and study plan

Primary outcomes

  1. ferritin concentration

    Time frame: 0-3 months

    ng/ml

  2. hepicidin concentration

    Time frame: 0-3 months

    ng/ml

Sponsors and collaborators

Lead sponsor

Fayoum University

Other

Registry information

Official study title

Decreased Ferritin And Increased Hepcidin Serum Levels In Periodontitis Patients With Diabetes Mellitus Type 2. Controlled Before-And-After Study

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
May 28, 2019
Registry last updated
Jun 11, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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