Serum Citrate in Diagnosis and Follow-up for Glaucoma

Glaucoma might be a mitochondria associated disease. Since citrate is a major component in mitochondrial metabolism its determination in blood might serve as a biomarker.

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Key information

Conditions

Glaucoma Eye Diseases Ocular Hypertension

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Basel

Basel, Canton of Basel-City, 4031, Switzerland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age> 18 years
glaucoma

Exclusion criteria

Active ocular inflammation
Ocular Hypertension
Nephropathy
Alcohol-, Drug abuse
Mitochondriopathy

Treatment and study plan

drawing blood sample

Procedure

fasting blood sample

Primary outcomes

serum citrate level

Time frame: 1

Secondary outcomes

urine citrate

Time frame: 1

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Collaborators

Kantonsspital Baselland Bruderholz

Registry information

Important dates

Study start: 2008
Primary completion: 2012
Study completion: 2013
First posted: Dec 8, 2008
Registry last updated: Jan 8, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed