Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07251036

Serum Chordecone Concentration in Guadeloupean Population: Impact of a Multidisciplinary Support Program on the Reduction of the Contamination Level.

The French West Indies (Guadeloupe, Martinique) are characterized by a major use of pesticides in bananas plantation from the 1950s. These crops used organochlorine insecticides and especially chlordecone (CLD) from 1972 to 1993. The lack of biotic and abiotic degradation of CLD led to persistent soil pollution, contamination of surface and deep waters, of numerous plant and animal, and of the population. The extent and persistence of CLD contamination over time is a major issue for these territories. An internal reference value (0.4μg/l) was recently determined. Although useful for a population approach, it must be used with caution for the interpretation of an individual result. In response to the strong social demand expressed by the population for access to free chlordecone blood tests, a screening program for blood chlordecone test was authorized by the 2019 French Finance Act.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre Hospitalier Universitaire de la Guadeloupe

Pointe-à-Pitre, Guadeloupe, 97159

Location status: Recruiting

Location contact

Eunice NUBRET

CONTACT

[email protected]

Jacqueline DELOUMEAUX, Doctor

PRINCIPAL_INVESTIGATOR

Valérie SOTER

CONTACT

[email protected]

+590590934686

About this study

The target populations will receive an invitation letter with an information notice and a consent form. The referral physician will explain the program and the research project and prescribe a standardized blood sample test.

Blood samples will be taken in one of the biology laboratories participating in the project. Serum chordecone test will be performed by the Pasteur Institute of Guadeloupe. Blood samples for biological collection will be sent to the Biological Resource Center, Karubiotec™. The result of the chlordécone level will be sent back to each subject with a recommendation note based on the chlordécone level value. Phone contact information for those who consented to the study will be forwarded to the research assistant for the questionnaire.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

  • All subject overs 18 years of age residing in Guadeloupe invited to participate to the program by the Regional Health Agency or subjects who requested a test from their doctor in the framework of the ministerial measure.
  • Subjects who have read the information note and signed the consent to participate in the study
  • Subjects with social security coverage

Exclusion criteria

  • Refusal to participate
  • Person not affiliated with a social security scheme
  • Person under legal protection (safeguard of justice, guardianship, curatorship, etc.

Treatment and study plan

CHLORGUA

Other

The target populations will receive an invitation letter with an information notice and a consent form. The referral physician will explain the program and the research project and prescribe a standardized blood sample test.

Blood samples will be taken in one of the biology laboratories participating in the project. Serum chordecone test will be performed by the Pasteur Institute of Guadeloupe. Blood samples for biological collection will be sent to the Biological Resource Center, Karubiotec™. The result of the chlordécone level will be sent back to each subject with a recommendation note based on the chlordécone level value. Phone contact information for

Primary outcomes

  1. chlordecone level

    Time frame: between Day0 to Day15

    ug/l

  2. risk factors

    Time frame: between day 15 and day 45 ,

    chlordeconemia survey

Secondary outcomes

  1. chlordecone level

    Time frame: At 9 months after intervention

    ug/l

  2. chlordecone level

    Time frame: At 18 months after intervention

    ug/l

  3. chlordecone level

    Time frame: at delivery for pregnant women

    ug/l

  4. impact of an intervention

    Time frame: between day 15 to day 45, at month 9 and month 18

    chlordeconemia survey

Study contacts

Contact information is provided by the study sponsor or research team.

Eunice NUBRET

CONTACT

[email protected]

Valérie HAMONY-SOTER

CONTACT

[email protected]

+590590934686

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de la Guadeloupe

Other

Registry information

Acronym: ChlorGua

Important dates

Study start
2022
Primary completion
2028
Study completion
2028
First posted
Nov 26, 2025
Registry last updated
Nov 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.