Serum Carotenoids and Risk of Gastrointestinal Tract Cancer: Meta-analysis of Ten Studies

Previous studies have suggested that serum carotenoids may be associated with risk of gastrointestinal tract cancer (GIT cancer), but the results were inconsistent. Thus, the investigators conducted a meta-analysis to evaluate the associations between serum carotenoids and risk of GIT cancer.

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Key information

Conditions

Gastrointestinal Tract Cancer Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Neoplasms Neoplasms by Site

Sex eligibility

All sexes

Study type

Observational

Primary location

West China Hospital, Sichuan University

Chengdu, Sichuan, 610041, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The study had both case and control groups
Serum carotenoids levels, relative risk (RR) or OR and corresponding 95% CI were reported
Patients in case group were diagnosed with GIT cancer

Exclusion criteria

·Animal studies

Treatment and study plan

serum carotenoids

Other

In each study, the serum concentrations of carotenoids were detected by high performance liquid chromatography

Primary outcomes

Gastrointestinal Tract Cancer Incident Measure

Time frame: Through study completion, an average of 5 years.

The gastrointestinal tract cancer incident would be recorded during the follow-up years.

Sponsors and collaborators

Lead sponsor

Yong Zhou

Other

Collaborators

Sichuan Provincial Science and Technology Support Project (2016SZ0047)

Registry information

Important dates

Study start: 2017
Primary completion: 2017
Study completion: 2017
First posted: Feb 14, 2018
Registry last updated: Feb 22, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed