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NCT Number: NCT06727786

Serious Game to Teach Opioid Overdose Response

This study evaluates the efficacy of a serious game to teach students how to recognize and respond to opioid overdose

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Key information

Conditions

Opioid Overdose Chemically-Induced Disorders Drug Misuse Drug Overdose Mental Disorders Narcotic-Related Disorders Opiate Overdose Opioid-Related Disorders Prescription Drug Misuse Substance-Related Disorders

Age range

12 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

About this study

This study uses an interactive realistic film depicting an opioid overdose to teach high school/middle school students how to recognize and respond to opioid overdose. The film features a person who finds their friend unresponsive, with evidence of opioid use. The unresponsive friend demonstrates signs of opioid overdose. The hero must recognize opioid overdose, administer naloxone (opioid antedote) and perform CPR. The film is made interactive by the narrator pausing the action of the film, and asking learners to answer questions/make choices.

Efficacy is tested on the day of training, and 2-4 months later. Efficacy is measured by student ability to correctly administer naloxone to a manikin, perform CPR, and answer knowledge questions about opioid overdose. Other studied metrics include student engagement/enjoyment, attitudes/biases, and emotions created by the training. These will be tested through validated questionnaires.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Student at participating school, enrolled in Health or Science Class

Exclusion criteria

  • None

Treatment and study plan

Serious game training

Other

A serious game featuring a dramatic/realistic film, pauses with questions for active learning, and practice administration of naloxone and performing CPR

Primary outcomes

  1. Naloxone administration Skill

    Time frame: Day of training, and 2-3 months

    Properly administer naloxone to a victim of opioid overdose Study personnel will ask students to administer naloxone to a CPR manikin. Personnel will use a checklist from the Center for Addiction and Mental Health to score student responses.

Secondary outcomes

  1. CPR Skill

    Time frame: Day of training, and 2-3 months

    Ability to perform high-quality CPR Students will be asked to perform CPR on a CPR manikin for 2 minutes. CPR skill will be measured with the CPR Meter 2 from Laerdal, which reports compression rate, depth, and percent recoil. We will consider "high quality CPR" students who perform 70% or more of compressions at appropriate rate (100-120/min), depth (2-2.5inches), and full recoil.

  2. Attitudes towards opioid overdose

    Time frame: Day of training, and 2-3 months

    Attitudes, enjoyment, and emotions towards opioid overdose

    Emotions will be measured using the PANAS scale (Positive And Negative Affect Scale) which consists of 10 positive and 10 negative emotion words. The total score is calculated by finding the sum of the 10 positive items, and then the 10 negative items. Scores range from 10 - 50 for both sets of items. For the total positive score, a higher score indicates more of a positive affect.

    Engagement and enjoyment will be measured using Likert-style questions asking for agreement with statements such as "I enjoyed CPR training," "CPR training was fun," "I will use CPR training in the future," "It is important to learn CPR"

    Attitudes will be measured with a custom questionnaire asking Likert-style responses to statements regarding opioid overdose.

  3. Knowledge of opioid overdose response

    Time frame: Day of training, and 2-3 months

    Knowledge of how to recognize and respond to opioid overdose A questionnaire of custom-created multiple choice questions will assess student knowledge of how to recognize and respond to opioid overdose.

Study contacts

Contact information is provided by the study sponsor or research team.

Associate Professor, MD

CONTACT

[email protected]

7756828239

Sponsors and collaborators

Lead sponsor

University of Nevada, Reno

Other

Registry information

Official study title

Using a Serious Game to Teach People How to Recognize and Respond to Opioid Overdose

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Dec 11, 2024
Registry last updated
Dec 11, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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