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OpenTrials
Completed

NCT Number: NCT03630900

Sequential Versus Single O2 Levels on Human Embryo Development

Myriads of elements affect human embryo culture in vitro. These include, but not limited to, air quality, culture media, culture temperature, incubator humidity, pH, and O2 levels. O2 tension has been thoroughly investigated and, to date, 5% O2 level is superior to 20%. Reports showed that lowering the O2 from Day 3 of embryo culture seems to be physiological.

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Key information

Conditions

Embryo Culture

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Qena Fertility Center, Qina, Qena Governorate, Egypt

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ICSI cycles undergoing their first ICSI attempt

Exclusion criteria

  • ICSI cycles with a previous failure

Treatment and study plan

Sequential O2 Culture

Other

We investigate the effect of sequential O2 levels on human embryo culture after Intracytoplasmic sperm injection (ICSI)

Primary outcomes

  1. Ongoing Implantation rate

    Time frame: three months

    number of sacs with a heartbeat after week twelve of gestation

Secondary outcomes

  1. clinical and ongoing pregnancies

    Time frame: three months

    registered pregnancy with fetal heartbeat at week four after transfer and after week twelve of gestation

  2. human embryo development in vitro

    Time frame: three months

Sponsors and collaborators

Lead sponsor

Ibn Sina Hospital

Other Gov

Collaborators

  • Banoon IVF Center

Registry information

Official study title

5% O2 or Lower is the Ideal Tension for Culturing Human Embryo Development From Day 3 Onward

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Aug 15, 2018
Registry last updated
Jul 16, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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