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OpenTrials
Completed

NCT Number: NCT02642783

Sensory Properties of Bowel Cleansing Solutions

Samples of 4 commercially available bowel cleansing solutions, namely PEG-electrolyte + ascorbic acid (PEG-Asc, Moviprep®, Norgine, UK), PEG-electrolyte (PEG, Fortrans® Ibsen, France), sodium picosulfate/magnesium citrate (SPS, Picoprep®, Ferring, Switzerland), and oral sodium sulfate (OSS, Izinova®, Ibsen, France) were prepared according to the manufacturer's instructions. Descriptive analysis was conducted with trained panelists (N= 14) to create a sensory profile for the solutions and generated attributes were rated on an unstructured 15-cm line scale using the Compusense at-hand® (Guelph, Canada) sensory evaluation software. Acceptability testing was carried out with untrained participants (N=80) and samples were rated on the 9-point hedonic scale. Moreover, a Just-About-Right (JAR) scale was included for the four basic tastes to determine their compatibility with optimum taste/acceptability levels in the products.

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Key information

Conditions

Laxative Bowel Cleansing Solutions

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age between 18 and 50 years

Exclusion criteria

  • allergies to polyethelene glycol (PEG), artificial sweeteners

Treatment and study plan

Descriptive analysis

Behavioral

subjects were asked to assess the sensory profile by tasting the laxative bowel cleansing solutions, namely: Moviprep, picoprep, fortrans and isinova

acceptability test

Behavioral

subjects were asked to assess the acceptability of the laxative bowel cleansing solutions, namely: Moviprep, picoprep, fortrans and isinova

Primary outcomes

  1. rating of sensory attributes

    Time frame: 3 weeks

    participants attended 4 training sessions during which they generated sensory descriptive attributes specific for the tasted laxative solutions. In addition, they evaluated the laxative samples by rating generated attributes on a 15-cm unstructured line scale using compusense at-hand sensory evaluation software.

Secondary outcomes

  1. Acceptability Score

    Time frame: 1 week

    untrained participants evaluated the laxative samples for acceptability testing using the 9-point hedonic scale.

  2. Just about right score

    Time frame: 1 week

    Participants evaluated the laxative samples for the 4 basic tastes (saltiness, sourness, sweetness and bitterness) to determine their compatibility with optimum taste levels in the products.

Sponsors and collaborators

Lead sponsor

American University of Beirut Medical Center

Other

Registry information

Official study title

Sensory Evaluation of Laxative Bowel Solutions Used Prior to Colonoscopy

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Dec 30, 2015
Registry last updated
Dec 30, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.