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Completed

NCT Number: NCT06882642

Sensory Integration Therapy in a Sample of Children With Autism Spectrum Disorder

The objective of this study is to determine the effects of therapy in sensory rooms with multisensory environment on the severity of autism spectrum disorder and stereotyped and repetitive behaviours in a sample of Egyptian children with autism spectrum disorder

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Key information

Age range

3 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain Shams University

Cairo, 11591, Egypt

About this study

Autism Spectrum Disorder is a neurodevelopmental disorder characterized by deficits in social interactions, social communication and stereotyped behaviours associated with sensory disorders occurring before the age of 3.

According to DSM-5, sensory processing disorders include hyper-reactivity to sensory stimuli which is an adverse response to sensory stimuli (specific sounds or textures, excessive smells), hypo-reactivity as an apparent indifference to sensory stimuli (pain or temperature-hot/cold) and sensory seeking as a strong desire for sensory intake (touching of objects, visual fascination with lights and movements) or unusual sensory interests in the environment.] Multisensory interactions in spatial processing are investigated with functional neuroimaging and electrophysiological recordings. Using fMRI, researchers identified candidate multisensory areas by looking for regions of cortex that are activated by visual and tactile stimuli, showing that multisensory processing in the human brain involves the multisensory areas of ''association'' cortex as well as the modality-specific areas of cortex that are specialized for the processing of stimulus features such as colour, shape and texture.

Ayres Sensory Integration therapy (ASI) is an individualized intervention designed to address the specific underlying sensory-motor issues that may be affecting children's performance during daily routines and activities, including participation within the classroom and in other contexts of the school.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients included in the study are diagnosed with Autism spectrum disorder according to DSM-V criteria.
  • Participants have to have a sensory problem in their diagnostic criteria.
  • Age ranges between 3-10 years. (as scope of the study is focused on children)
  • Both males and females.
  • Parents or guardian agreed to informed consent.

Exclusion criteria

  • Parents refusing to participate in the research
  • Children with comorbid psychiatric and/or neurological disorder
  • Children with co-morbid sensory deficit, hearing , vision, and motor deficit
  • Intelligence quotient level below 60
  • Children who scored typical performance in the sensory profile care-giver questionnaire

Treatment and study plan

Sensory integration therapy

Procedure

Autistic patients will undergo sensory integration therapy

Primary outcomes

  1. Effect of sensory integration therapy

    Time frame: 12 weeks

    Effect of sensory integration therapy on autism spectrum disorder symptoms and signs and severity. The sessions are held weekly for 12 weeks, lasting half an hour, and the measurement is done before and after them, taking an hour. The sensory integration program lasts 12 weeks with 12 sessions, each 30 minutes. Participants must attend at least 9 sessions. Afterward, they will be reassessed using CARS and the Sensory Profile Caregiver questionnaire. The sensory room provides multisensory stimulation through tools like projectors, fibre optics, and auditory devices.

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Sensory Integration Therapy in a Sample of Children With Autism Spectrum Disorder; an Outcome Study

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Mar 18, 2025
Registry last updated
May 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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