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Completed

NCT Number: NCT01529398

Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis

People with knee osteoarthritis (OA) have functional instability and defective neuromuscular function, it was recently suggested that sensorimotor exercises may be important and needed to improve the effectiveness of training programs for these patients. This study objective was to compare the effectiveness of a supervised resistance muscular training (RT) versus sensorimotor training (SMT) for patients with Knee OA, on decrease of pain and functional improvement.

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Key information

Conditions

Knee Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Rheumatic Diseases

Age range

50 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Department of Rheumatology and Physiotherapy of Interlagos Ambulatory - Santo Amaro University

São Paulo, 04815-180, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with tibiofemoral osteoarthritis;
  • Both genders;
  • Age> 50 years <75 years;
  • Completion of clinical and radiological criteria of the American College of Rheumatology (ACR) criteria for knee OA;
  • No physical activity in the previous 3 months;
  • Education level from the 4th grade of primary school.

Exclusion criteria

  • uncontrolled hypertension;
  • decompensated diabetes mellitus;
  • uncontrolled thyroid diseases;
  • cardiorespiratory disease (ischemia, arrhythmia, chest pain, or exercise-induced bronchospasm), liver abnormalities;
  • Patients with grade IV functional limitation that needed devices to walk(Kellgren-Lawrence radiographic classification);
  • Patients in a period of sick leave by the INSS or any other related factor;
  • Other rheumatic diseases.

Treatment and study plan

Sensorimotor training (SMT)

Other

The group realized 16 weeks of sensorimotor training, twice a week, with duration of 30 minutes each session. The intervention included agility and coordination exercises, perturbation training and stretching exercises. Also, the participants received orientation about the knee osteoarthritis.

Other names: Agility/perturbation training; proprioceptive training; neuromuscular training

Resistance Training (RT)

Other

The group realized 16 weeks of resistance training for the quadriceps and hamstring muscles, twice a week, with duration of 30 minutes each session. The intervention included strength leg raises, simple quadriceps and hamstring strengthening with cuff weights realized in 3 sets of ten repetition maximum(10RM) for each muscle group. The group also realized stretching exercises for lower limbs and received orientation about the knee osteoarthritis.

Control group (CG)

Other

Patients in this group also received information about knee osteoarthritis and realized the same warm-up and cool-down intervention realized in the interventional groups. During 16 weeks they went to the ambulatory twice a week to perform 5 minutes of stationary bicycle and 5 minutes of stretching exercises for lower limbs.

Primary outcomes

  1. Visual analogue scale of pain (VAS)

    Time frame: 16 weeks

  2. Get Up and Go Test

    Time frame: 16 weeks

Secondary outcomes

  1. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

    Time frame: 16 weeks

  2. electromyographic analysis of quadriceps muscle (EMG)

    Time frame: 16 weeks

  3. isometric quadriceps strength

    Time frame: 16 weeks

  4. Medical Outcomes Study Short Form (SF-36)

    Time frame: 16 weeks

    Generic, patient-report measure designed to assess health-related quality of life, comprises 36 items divided into 8 subscales.

    • Physical Functioning
    • Role Limitations due to Physical Problems
    • General Health Perceptions
    • Vitality
    • Social Functioning
    • Role Limitations due to Emotional Problems
    • General Mental Health
    • Health Transition

  5. Berg Balance Test

    Time frame: 16 weeks

  6. Tinetti Test

    Time frame: 16 weeks

  7. activities of daily living scale (ADLS)

    Time frame: 16 weeks

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Registry information

Official study title

Efficacy of a Sensorimotor Training in Patients With Knee Osteoarthritis: a Randomized Clinical Trial

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Feb 8, 2012
Registry last updated
Feb 9, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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