Selpercatinib and Body Composition | Clinical Trial

Key information

Conditions

Thyroid Cancer Endocrine Gland Neoplasms Endocrine System Diseases Head and Neck Neoplasms Neoplasms Neoplasms by Site Thyroid Diseases Thyroid Neoplasms

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital of Pisa

Pisa, PI, 56124, Italy

About this study

investigation of body composition by DXA

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults (≥18 years old)
Diagnosis of thyroid cancer
Ongoing treatment with selpercatinib

Exclusion criteria

Inability to provide informed consent

Treatment and study plan

observation in patient under treatment

Other

observation in patient under treatment

Selpercatinib

Drug

observational study of patients under selpercatinib

Primary outcomes

Total lean mass assessed by DXA (kg)

Time frame: Baseline and 12 months

Total lean body mass measured by dual-energy X-ray absorptiometry

Secondary outcomes

24-hour energy expenditure (kcal/day)

Time frame: Baseline and 12 months

Total energy expenditure measured over 24 hours using a whole-room indirect calorimeter

Sponsors and collaborators

Lead sponsor

University of Pisa

Other

Registry information

Acronym: EECRTKI

Important dates

Study start: 2024
Primary completion: 2026
Study completion: 2026
First posted: Apr 22, 2026
Registry last updated: Apr 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed