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NCT Number: NCT06497868

Self-compassion and Bipolar Disorder

Currently, pharmacotherapy is central in the management of bipolar disorder (BD), but does not guarantee satisfactory results for many patients. Existing psychotherapies, notably cognitive-behavioral therapy (CBT), show some effectiveness, but do not target the mechanisms that maintain the disorder. Indeed, people with BD present a low level of self-compassion, suffer from comorbidities (e.g. anxiety, depression), and have a high level of emotional dysregulation, which can contribute to increasing the risk of relapse and mood instability.

In this context, it has been suggested that interventions targeting self-compassion could reduce BD psychopathology and strengthen emotional regulation skills.

Two psychological therapies targeting self-compassion could be promising in the treatment of BD: Compassion-Based Therapy (CBT) and Cognitive Therapy focused on Mental Imagery (mTCI). These approaches partly emphasize compassionate mental imagery to promote self-soothing and emotion management skills.

Studies on the feasibility and effectiveness of CBT and mTCI in the context of BD are few in number, and do not focus on their impact on emotional regulation abilities. Evaluating these therapies could lead to the development of more specific and effective interventions for people with TB.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Service de Psychiatrie - CHU de Strasbourg - France

Strasbourg, Les Hôpitaux Universitaires de Strasbourg, 67091, France

Location status: Recruiting

Location contact

Emilie CHARLES, Psychologist

SUB_INVESTIGATOR

Luisa WEINER, Psychologist

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Major subject (≥ 18 years old)
  • Subject with diagnosed bipolar disorder followed on an outpatient basis, in a day hospital or outside the hospital during the period from January 1, 2022 to February 29, 2024.
  • Absence of written opposition in the subject's medical file to the reuse of their data for scientific research purposes.

Exclusion criteria

  • Subject having expressed his opposition to the reuse of his data for scientific research purposes.
  • Judicial measures: care under constraint or patient deprived of liberty due to a legal measure

Treatment and study plan

Primary outcomes

  1. Evaluation of the effectiveness of the Compassion-Based Therapy (CBT) and the Cognitive Therapy focused on Mental Imagery (mTCI).

    Time frame: Up to 1 year

    For the evaluation of these two psychological therapies targeting self-compassion, the Self Compassion Scale (SCS; Neff, 2003) will be used :

    • The SCS is a 26-question self-assessment questionnaire with a response format of 5-point Likert type (from 1= almost never to 5= almost always).
    • The score between :
    • 1.0-2.49 is considered to be low,
    • 2.5-3.5 is considered to be moderate,
    • 3.51-5.0 is considered to be high.

Study contacts

Contact information is provided by the study sponsor or research team.

Luisa WEINER, PhD

CONTACT

[email protected]

33 3 88 11 65 11

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Official study title

Self-compassion and Bipolar Disorder: Evaluation of the Feasibility and Preliminary Effectiveness of Two Psychological Therapies Targeting Self-compassion

Acronym: COMPASS-TB

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 12, 2024
Registry last updated
Jul 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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