Skip to main content
OpenTrials
Completed

NCT Number: NCT04370132

Segment IV Hypertrophy After Liver Venous Deprivation

before major hepatectomy, in case of insufisant future liver remanent volume or function, portal embolization is a routinely used method to enable growth of the future liver remnant. Recently liver venous deprivation has been described in some pioneer centre. The results are processing with greater and faster hypertrophy allowing probably less drop out from the embolization to surgery compared to portal embolization.

In major hepatectomy, and specially in right or extended right hepatectomy the segment IV plays an important role in the proportion of future liver remnant.

Despite the growing interest in the scientific community for liver venous deprivation many aspects concerning the liver hypertrophy remains unexplored. In particular the the degree of hypertrophy of segment IV after liver venous deprivation compared to portal embolization.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Major Hepatectomy

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Uh Montpellier

Montpellier, 34295, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patient with liver tumor selected for right hepatectomy with insufficient future liver remnant who have undergoes portal embolization or liver venous deprivation

Exclusion criteria

  • left / extended left hepatectomy

Treatment and study plan

Primary outcomes

  1. segment IV degree of hypertrophy

    Time frame: 1 day

    segment IV degree of hypertrophy

Secondary outcomes

  1. overall survival

    Time frame: 5 years

    overall Survival : overall survival : is overall survival from date of hepatic surgery until the 01/04/2020 or during 5 years

  2. recurrence free survival

    Time frame: 5 years

    recurrence free Survival : is the the survival without same deasese recurrence from the hepatic surgery date until the 01/04/2020 or during 5 years

Sponsors and collaborators

Lead sponsor

University Hospital, Montpellier

Other

Registry information

Official study title

Segment IV Hypertrophy After Liver Venous Deprivation Compared to Portal Embolization in Patient Before Major Hepatectomy

Important dates

Study start
2015
Primary completion
2020
Study completion
2020
First posted
Apr 30, 2020
Registry last updated
Apr 30, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.