University of North Carolina
Chapel Hill, North Carolina, 27599, United States
NCT Number: NCT02483559
The purpose of the study is to test the use of amber glasses at night as a method to block blue light from the eye, allowing the brain to produce a dim-light melatonin onset. The investigators hypothesize that blue-blocking will produce measurable benefits in subjectively and objectively rated sleep quality and mood as well as salivary melatonin levels during the night.
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Notify Me18 year–50 year
All sexes
Interventional
Not applicable
Chapel Hill, North Carolina, 27599, United States
Participants will complete a self-report battery containing measures of sleep quality, morningness-eveningness chronotype, and mood. Participants will then wear a wrist-worn accelerometer for 14 days to objectively record activity level and sleep quality. Participants will also fill out a daily sleep log and short self-report measures assessing sleep and mood. On days 4-7 and 11-14 of the study the participants will wear either amber or placebo control lenses prior to sleep onset in a randomized crossover design (i.e., participants will be randomized to wear either amber lenses or placebo lenses for the first part of the protocol and then switch to wear the opposite lenses for the second part of the protocol). Participants will spend nights 7 and 14 of the study in a sleep laboratory in order to obtain hourly melatonin samples and wear a wrist sleep monitor to non-invasively and objectively measure sleep state and quality using peripheral arterial tone and oxygen perfusion.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Glasses fitted with amber lenses that block the blue spectrum of light (~470 nm) to be worn prior to desired sleep onset time.
Glasses fitted with placebo lenses that allow all visible spectrum of light to be worn prior to desired sleep onset time.
Time frame: 4 days
Hourly saliva samples will be collected from participants at the end of each 4 night interval in order to measure levels of melatonin production.
Time frame: 4 days
Participants will complete the Positive and Negative Affect Scale (PANAS) on a daily basis to measure self-reported mood.
Time frame: 4 days
Participants will complete nights in the sleep lab while wearing a watch device to measure arterial tone in order to objectively measure time spent in different sleep stages.
Time frame: 4 days
Participants will complete the Leeds Sleep Evaluation in order to assess self-report of sleep quality.
University of North Carolina, Chapel Hill
Other
Seeing the World Through Assorted Glasses (SWAG)
Acronym: SWAG
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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