Search for Biomarkers in Human Glaucoma: Lymphocytes Alterations and Rate of Progression

The aim of this study was to evaluate the lymphocyte phenotype in primary open- angle glaucoma (POAG) patients compared to healthy subjects of the same age, in order to confirm the importance of immune responses in glaucoma and the possible correlation to the severity of the disease.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Glaucoma, Open-Angle Eye Diseases Glaucoma Ocular Hypertension

Age range

19 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Azienda ospedaliera universitaria

Parma, 43100, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinical diagnosis of primary open-angle glaucoma
age between 19 an 85 years old

Exclusion criteria

age less than 19 or more than 85 yrs
positive history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection and (e) diabetes, (f)systemic inflammation

Treatment and study plan

Primary outcomes

compare the lymphocyte phenotype of POAG patients to healthy subjects of the same age

Time frame: the same day of bloodwithdrawal

Secondary outcomes

correlate the immunophenotype of POAG patients to the severity of disease

Time frame: within 3 months after blood withdrawal

Sponsors and collaborators

Lead sponsor

University of Parma

Other

Registry information

Official study title

Search for Biomarkers in Human Glaucoma: Possible Correlations Between Alterations in Peripheral Lymphocytes and Disease Severity

Important dates

Study start: 2007
Primary completion: 2007
Study completion: 2008
First posted: Sep 22, 2009
Registry last updated: Sep 22, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed