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NCT Number: NCT05291728

Screening for Early Gastric Cancer in Shaanxi Province

This study collect the relevant data of local residents over 20 years old in 11 regions of Shaanxi Province, The basic information of the subjects was collected by filling in the questionnaire, and serum helicobacter pylori antibody detection was completed at the same time. The expert group determined the high-risk population of gastric cancer after comprehensive evaluation. All the high-risk population of gastric cancer without contraindications underwent electronic gastroscopy in the designated hospital after signing the informed consent. By collecting and analyzing data, early gastric cancer screening was completed and a new gastric cancer risk assessment model was established to evaluate the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as helicobacter pylori infection, radical treatment and recurrence rate.

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Key information

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The second affiliated hospital of xi'an jiaotong university

Xi'an, Shaanxi, 710004, China

Location status: Recruiting

Location contact

Jinhai Wang, MD

CONTACT

[email protected]

+86-29-13609281113

About this study

From October 2020 to October 2026, after obtaining the informed consent of local residents over 20 years old in 11 regions of Shaanxi Province, the subjects' social demographic characteristics, living and eating habits, and previous diseases were collected by filling in questionnaires, and serum helicobacter pylori antibody was detected at the same time. After comprehensive assessment by the expert group, the high-risk population of gastric cancer was determined. All high-risk population of gastric cancer without contraindications underwent electronic gastroscopy in designated hospitals after signing informed consent. By collecting and analyzing data, early gastric cancer screening was completed and a new gastric cancer risk assessment model was established to evaluate the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as helicobacter pylori infection, radical treatment and recurrence rate. In this project, the research group was responsible for formulating the plan, designing the questionnaire, and conducting quality control and grass-roots guidance tour. Guanghua Science and Technology Foundation provided public welfare assistance, and distributed and collected questionnaires with the assistance of grass-roots clinics. Finally, the research group sorted out and analyzed the data.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Local resident over 20 years old.
  • Obtain verbal informed consent of the subject.

Exclusion criteria

  • Refused to participate in this research project.
  • Questionnaires or serological tests for helicobacter pylori antibodies were not completed.
  • This study was not completed due to other reasons.

Treatment and study plan

Primary outcomes

  1. the detection rate of early gastric cancer

    Time frame: 2020.10.01-2026.10.01

    Patients at high risk of gastric cancer were assessed by questionnaire and Hp test results, and then underwent gastroscopy.Then analyse the detection rate of early gastric cancer.

Secondary outcomes

  1. the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as the prevalence of helicobacter pylori infection, radical treatment and recurrence rate.

    Time frame: 2020.10.01-2026.10.01

    Basic information, Hp antibody detection results and gastroscopy results were collected,and then analyse the prevalence of dyspepsia, gastroesophageal reflux disease and precancerous lesions in the natural population of Shaanxi Province, as well as the prevalence of helicobacter pylori infection, radical treatment and recurrence rate.

Study contacts

Contact information is provided by the study sponsor or research team.

Rui Wang, MD

CONTACT

[email protected]

15513872291

jinhai Wang, MD

CONTACT

[email protected]

029-87679335

Sponsors and collaborators

Lead sponsor

Second Affiliated Hospital of Xi'an Jiaotong University

Other

Registry information

Important dates

Study start
2020
Primary completion
2026
Study completion
2026
First posted
Mar 23, 2022
Registry last updated
Mar 23, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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