Screening for Atherotic Plaques by Ultrasound for Assessing Cardiovascular Risk

Cardiovascular disease is a common diagnosed and treated condition in private practices of primary health care. There is growing evidence that atherosclerotic plaques as predictors for stroke and heart attack are more prevalent than expected based on the clinical score in people with low risk for stroke and heart attack .

Diagnosing atherosclerotic plaques can help to decide if a lipid lowering therapy should be prescribed even if the clinical risk score is low or on the other hand if they can be observed even in high lipid levels.

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Key information

Conditions

Atherosclerosis of Artery

Age range

41 year–72 year

Sex eligibility

All sexes

Study type

Observational

About this study

Both common and proximal internal carotid arteries and both common femoral arteries (including bifurcations) were screened by ultrasound in patients who came for a check-up to a primary care practice with no known cardiovascular disease and low risk for stroke and heart attack according to the AGLA/GSLA risk score which is mostly used in Switzerland.

All patients agreed and gave written informed consent to be included in this study. Presence of plaques was defined as a focal carotid intima-media thickness >0.5 cm on ultrasound. Screening was performed by a medical doctor (DP) certified for the procedure using the following ultrasound system: Toshiba Nemio XG, probe 7.5 MhZ.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

low cardiovascular risk assessed by the AGLA/GSLA-score

Exclusion criteria

cardiovascular disease

Treatment and study plan

ultrasound guided detection of atherosclerotic plaques

Diagnostic Test

screening by ultrasound of atherosclerotic plaques

Primary outcomes

Prevalence of plaques in cardiovascular low risk population

Time frame: 1 year

Number of participants with the presence of carotid and/or femoral atherosclerotic plaques diagnosed via ultrasound (defined as a focal intima-media thickness >0.5 cm on ultrasound).

Sponsors and collaborators

Lead sponsor

Cabinet de Medecine Interne Générale Demetrio Pitarch

Other

Registry information

Official study title

Prevalence of Atherosclerotic Carotid and/or Femoral Plaques in Patients Without Known Cardiovascular Disease and at Low-risk for Major Cardiovascular Events (AGLA/GLSA Score) Visiting a Private Primary Healthcare Practice in Switzerland

Important dates

Study start: 2016
Primary completion: 2016
Study completion: 2016
First posted: Apr 17, 2018
Registry last updated: Apr 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed