Scheduled Autologous PRP Guided Injection in the Maxillary Bony Defects

The study aims to detect the effect of scheduled autologous platelet-rich plasma- guided injection in the healing process of critical-sized maxillary bony defects after surgical removal of non-malignant lesions by using bone volumetric analysis and density measuring with cone beam computed tomography.

Inclusion criteria

• Age: 18-65 years (adults within a specific age range).

Diagnosis: Non-malignant maxillary bony defects (e.g., benign tumors or cysts).

Health: Generally healthy participants who can tolerate surgery.

Platelet Function: No platelet disorders or blood-related conditions.

Willingness: Informed consent and ability to follow the protocol.

No Use of Blood Thinners: No current use of anticoagulants like aspirin.

Exclusion criteria

• Age: Children (under 18) and elderly (over 75).

Malignant Lesions: Participants with cancer or pre-cancerous conditions.

Systemic Illness: Severe conditions (e.g., uncontrolled diabetes, autoimmune disorders).

Platelet Disorders: Low platelet count or bleeding disorders (e.g., hemophilia).

Infections: Active infections or inflammatory conditions (e.g., periodontal disease).

Pregnancy: Women who are pregnant or breastfeeding.

Recent Surgery/Trauma: Recent maxillary surgery or trauma.

Uncontrolled Medications: Use of blood thinners, NSAIDs, or immunosuppressive drugs.

Non-compliance: Unwillingness or inability to follow-up with the protocol.

Substance Abuse: Active drug or alcohol abuse.