Saving Limbs After Cancer: Blood Vessel and Soft Tissue Reconstruction Following Sarcoma Surgery in the Legs

This study aimed to evaluate whether immediate reconstruction of blood vessels and soft tissues can safely and effectively preserve limbs in patients undergoing surgery for sarcomas involving major arteries or veins in the arms or legs. The goal was to determine if this complex surgical approach helps avoid amputation, ensures good cancer control, and leads to acceptable complication rates and healing outcomes.

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Key information

Conditions

Soft Tissue Sarcoma (STS) Neoplasms Neoplasms by Histologic Type Neoplasms, Connective and Soft Tissue Sarcoma

Sex eligibility

All sexes

Study type

Observational

Primary location

Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Européen Georges Pompidou

Paris, 75, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All consecutive patient presented with STS with major vessels involvement

Exclusion criteria

All STS without major vessels involvement

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

1- Limb salvage rate 2- Flap survival 3- Vascular patency

Time frame: At 12 months postoperatively
- Limb salvage: Determined by clinical documentation of limb preservation without major amputation.
- Flap survival: Determined by clinical evaluation of flap viability
- Vascular patency: Determined by duplex ultrasonography or CT angiography.

Sponsors and collaborators

Lead sponsor

European Georges Pompidou Hospital

Other

Registry information

Official study title

Immediate Vascular and Soft Tissue Reconstruction After Sarcoma Resection Involving Major Limb Vessels: Early and Midterm Outcomes From a Tertiary Center

Acronym: SARCOVASCPLAST

Important dates

Study start: 2019
Primary completion: 2024
Study completion: 2024
First posted: Jul 30, 2025
Registry last updated: Jul 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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