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OpenTrials
Enrolling by Invitation

NCT Number: NCT07164144

SAVE: School Ambassadors for Vaccine Education

Influenza is associated with millions of cases of school absenteeism due to illness, hundreds of hospitalizations and thousands of deaths in the U.S. each year, which can be greatly reduced with influenza vaccination.

The goal of this randomized controlled trial is to learn if training school personnel in vaccine communication techniques and equipping schools with vaccine promotional materials targeting students and their parents/guardians increases the influenza vaccination rates of the student population within participating schools.

The main question it aims to answer is:

-Will flu vaccination rates be higher in intervention schools compared to control schools by the end of the intervention period?

Participating schools will:

* Have select school personnel (school nurses, coaches, teachers, etc.) complete an online training module and optional training workshop focused on vaccine communication [intervention arm only] * Utilize vaccine promotional materials (posters, flyers, digital files for social media, etc.) provided by the study team during flu season [intervention arm only] * Track student vaccination rates [intervention + control arm]

Enrolling by Invitation

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Key information

Age range

5 year–21 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Public Schools

Rochester, New York, 14614, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A student enrolled in a participating school (intervention or control) for at least two years

Treatment and study plan

Vaccine Communication Training

Behavioral

School personnel receive vaccine communication training + promotional materials

Primary outcomes

  1. Flu vaccination rate

    Time frame: 8 months (one flu season August-March)

Sponsors and collaborators

Lead sponsor

University of Rochester

Other

Collaborators

  • Centers for Disease Control and Prevention

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Sep 9, 2025
Registry last updated
Mar 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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