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OpenTrials
Completed

NCT Number: NCT01731197

Satiating Effects of Isolated Soy Proteins

Proteins are known to be more satiating than the other macronutrients; however, the type and amount of protein needed to induce a significant effect on satiety (fullness between meals) is sometimes difficult to determine. In this study, 2 differentially processed isolated soy proteins will be tested for satiety using subjective visual analogue scales. The amount of food consumed following intake of the isolated soy proteins will be measured 3 hours after consuming the proteins. The hypothesis is that differentially processed isolated soy proteins will show unique satiety responses.

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Key information

Conditions

Weight Management Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Glycemic Index Laboratories

Toronto, Ontario, M5C2N8, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI between 20 and 30 kg/m2
  • Age between 18-65y
  • Unrestrained eater (score<12)
  • Regularly consume 3 meals per day
  • Moderate exercise (eg running, aerobics classes, other sports activities) of no more than 7 hours per week

Exclusion criteria

  • use of drugs that influence carbohydrate or lipid metabolism (eg. hypoglycemic agents, antibiotics taken less than 6 weeks before study entry, glucocorticoids, anti-diarrheal medication, weight loss medication, and anti-diabetic medication)
  • presence of any significant disease (eg gastrointestinal diseases, diabetes, a CVD event less than 12 weeks from study entry, current hepatic disease, etc)
  • use of special dietary treatments within 4 weeks of study (eg weight loss diet, extremely high or low carbohydrate/protein/fat diet, use of meal replacements more than once a day)
  • use of supplements within 1 week of study (does not include vitamin supplements or supplements which are routinely taken and were initiated 4 weeks before the study and which will be continued during the study period)
  • restrained eater (score>12)
  • weight change (absolute body weight change of ≥ 10%) within the previous 6 weeks
  • alcohol intake >2 drinks/day
  • food allergies of any kind
  • swallowing difficulties
  • exercising more than 7 hours per week

Treatment and study plan

Dry-Blended Beverage

Dietary Supplement

Primary outcomes

  1. Subjective Satiety

    Time frame: 3 hours

    Measure subjective satiety using visual analogue scales

Secondary outcomes

  1. Ad Libitum Food Intake

    Time frame: 30 minutes

    At the end of 3 hours after consuming test diets, measure the amount of food consumed for 30 mins

Sponsors and collaborators

Lead sponsor

DuPont Nutrition and Health

Industry

Registry information

Official study title

Comparison of the Satiating Effects of Differentially Processed Isolated Soy Proteins

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Nov 21, 2012
Registry last updated
Oct 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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