Salvaged Red Blood Cell Transfusion During Pancreatic Adenocarcinoma Operations

Inclusion criteria

• Provision of signed and dated informed consent form. Able to understand their disease and the exploratory nature of sRBC transfusion during surgery for this histology.
• Patient is 18 years of age or older
• Patient has a diagnosis of cytologically or pathologically confirmed pancreatic adenocarcinoma
• Patient has an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
• Patient has an American Society of Anesthesiologists (ASA) classification of physical health status of 1-4
• Life expectancy of greater than six months
• Hemoglobin > 8.9 g/dl
• Platelet count greater than 200,000/mm3
• International Normalization Ratio ≤1.8
• Total serum bilirubin ≤ 2 mg/dL
• Serum creatinine ≤ 1.5 mg/dl
• Recovered from any hematologic toxicity less than grade 3 from all prior chemotherapy or radiotherapy, and be at least 14 days past the date of their last treatment.

Exclusion criteria

• Concomitant medical problems that would place the patient at unacceptable risk for a major surgical procedure.
• History of congestive heart failure and/or an LVEF <40%.
• Metastases
• Active systemic infections, hematological diseases, coagulation disorders or other major medical illnesses of the cardiovascular, hepatic, renal, respiratory or immune system.
• Patients with transabdominal drains, or peripancreatic abscess or fluid collections on cross-sectional imaging.