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Recruiting

NCT Number: NCT06655012

Salmeterol Effect on Exercise Performance

The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.

Recruiting

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Key information

Conditions

Healthy

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

August Krogh Building

Copenhagen, 2100, Denmark

Location status: Recruiting

Location contact

Morten Hostrup, PhD

CONTACT

[email protected]

+4535321595

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Inclusion Criteria:
  • Age 18-40
  • Physically active >5 hours a week
  • Maximum oxygen uptake classified as high or very high

Exclusion criteria

  • Active smoker currently or within the past 5 years
  • Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
  • Chronic or acute illness deemed by the responsible study physician to affect the test parameters
  • Deviation from the study protocol
  • Lean mass index >21 kg/m²
  • Pregnancy
  • Smoker
  • Blood donation during the past 3 months

Treatment and study plan

Salmeterol

Drug

Participants are administered 200 µg salmeterol (8 puffs) from a MDI device

Placebo

Drug

Participants are administered placebo (8 puffs) from a MDI device

Primary outcomes

  1. Power output during sprint testing

    Time frame: Through study completion, an average on 2 weeks

    Power output measured in Watts during a sprint on a bike ergometer

Secondary outcomes

  1. Power output during time trial

    Time frame: Through study completion, an average on 2 weeks

    Mean power output measured in Watts during a time trial on a bike ergometer

Other outcomes

  1. Quadriceps strength

    Time frame: Through study completion, an average on 2 weeks

    Maksimal torque (Nm) achieved during isometric contraction

Sponsors and collaborators

Lead sponsor

University of Copenhagen

Other

Registry information

Official study title

The Muscle Anabolic Response to β2-adrenergic Stimulation

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Oct 23, 2024
Registry last updated
Apr 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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