Skip to main content
OpenTrials
Completed

NCT Number: NCT04958005

Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children

This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Early Childhood Caries

Age range

3 year–70 month

Sex eligibility

All sexes

Study type

Observational

Primary location

Sultan KELEŞ

Aydin, 09100, Turkey (Türkiye)

About this study

Fifty six children ( 28 with early childhood caries and 28 without early childhood caries ; age range 3-6 years) will be recruited for the study. Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded and saliva samples will be collected. Interleukin-32, Interleukin-10, Interleukin-6 and TNF-α will be analyzed in saliva samples by ELISA.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children with untreated early chilhood caries
  • Age between 3 and 6 years

Exclusion criteria

  • Having a systemic problem or mental retardation
  • Children with treated caries

Treatment and study plan

ELISA

Diagnostic Test

Enzim linked immunoabsorbant assay

Primary outcomes

  1. IL-32

    Time frame: Baseline

    Interleukin- 32 level

  2. IL-10

    Time frame: Baseline

    Interleukin- 10 level

Secondary outcomes

  1. IL-6

    Time frame: Baseline

    Interleukin- 6 level

  2. Tnf-Alpha

    Time frame: Baseline

    Tnf-alpha level

Sponsors and collaborators

Lead sponsor

Aydin Adnan Menderes University

Other

Registry information

Official study title

Evaluation of Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children With Early Childhood Caries.

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jul 12, 2021
Registry last updated
Oct 21, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.