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Completed

NCT Number: NCT03877341

Sagittal Parameters After Mono Segmental Lumber Fusion: Interbody Versus Postrolateral Fusion

To compare postoperative radiographic sagittal parameters after monosegmental lumbar fusion: posterior lumbar interbody fusion versus postrolateral fusion in treatment of lumbar spine instability

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Assiut University Hospitals

Asyut, Egypt

About this study

The term "spondylolisthesis" refers to slipping of a vertebra relative to an adjacent vertebra,and there are two mean types degenerative and lytic : Degenerative spondylolisthesis is secondary to osteoarthritis leading to facet incompetence and disc degeneration.This condition allows anterior translation of one vertebra on another. Spondylolysis is the break in the pars interarticularis and is the precursor of lytic spondylolisthesis which associated with a pars fracture When nonoperative care fails and surgery is being considered, the type of fusion should be tailored to the specific pathology being treated.So there are different operations to correct this instability like postrolateral fusion (PLF) and posterior lumber interbody fusion (PLIF) PLF decreases segmental motion in the posterior column, which presumably reduces facet joint pain.Theoretical advantages of PLIF include decompression of exiting nerve roots by distraction of the collapsed disc space, achievement of optimal fusion in relation to the load-bearing capacity of the vertebral bodies and possibly attainment of a better fusion rate

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patient older of 18 years old.
  • Patients with lytic spondylolisthesis
  • Low grade spondylolisthsis 1,2

Exclusion criteria

  • Traumatic spondylolysis
  • Previous spine surgery.
  • Patient younger 18 years old
  • High grade spondylolisthsis 3,4,5 - multiple levels spondylolithises

Treatment and study plan

Posterolateral Fusion

Procedure

Instrumented posterolateral fusion is a spinal surgery that combines bone graft fusion with the use of hardware like screws and rods to stabilize the spine, correct alignment, and promote successful fusion. It's used for various spinal conditions.

Other names: PLF

posterior lumbar interbody fusion

Procedure

Posterior lumbar interbody fusion (PLIF) is a spinal surgery that involves removing problematic discs, inserting bone graft material, and sometimes a spacer, to promote fusion and stabilize the spine.

Other names: PLIF

Primary outcomes

  1. Spino sacral angle

    Time frame: 6month post op

    Which is the angle fromed between the line from front side of t1 to the middle of sacrum and the line passing through the sacral plateau

Secondary outcomes

  1. T1 pelvic angle

    Time frame: Pre op. Post op immediately. 6month post op

    The angle between the line from centroid of t1 to the femoral head axis and the line from femoral head axis to middle of the s1 end plate

  2. Pelvic incidence

    Time frame: Pre op. Post op immediately. 6month post op

    Is the angle between the line perpendicular to the s1 end plate from the midpoint of the end plate and the connecting line from the midpoint of the s1 end plate to center of the femoral head

  3. Pelvic tilt

    Time frame: Pre op. Post op immediately. 6month post op

    Is the angle between the connecting line from the midpoint of the s1 end plate to the center of the femoral head and the vertical line

  4. Sacral slope

    Time frame: Pre op. Post op immediately. 6month post op

    Is the angle between the tangent and the horizontal line of s1 end plate

  5. Lumbar lordosis

    Time frame: Pre op. Post op immediately. 6month post op

    Is the junction of the thoracic kyphosis to the s1 end plate

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2019
Primary completion
2023
Study completion
2023
First posted
Mar 15, 2019
Registry last updated
Sep 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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