Safety Study of a Refrigerator-stable Formulation of VARIVAX®

Inclusion criteria

• Healthy infants from 12 months of age to 15 months of age.
• Consent form signed by both parents or by the legal representative(s), properly informed about the study,
• Parent(s) able to understand the protocol requirements and to fill in the Diary Card.

Exclusion criteria

• Prior receipt of measles, mumps, rubella or varicella vaccine either alone or in combination vaccine,
• Known or suspected clinical history of infection with measles, mumps, rubella, varicella or zoster,
• Any known recent (≤30 days) exposure to measles, mumps or rubella,
• Any known recent (≤30 days) exposure to varicella or zoster involving:
• Any recent (≤3 days) history of febrile illness (rectal temperature ≥38.0°C),
• Active untreated tuberculosis,
• Any known blood dyscrasia, leukemia, lymphomas of any type, or other malignant neoplasms affecting the bone marrow or lymphatic systems,
• Any immune impairment or humoral/cellular deficiency, neoplastic disease or depressed immunity,
• Any previous (≤150 days) receipt of immune serum globulin or any blood-derived products or scheduled to be administered through visit 3,
• Any recent receipt of an inactivated or a live vaccine (≤ 30 days) or scheduled vaccination through visit 3