Safety of REPEVAX® Given One Month After REVAXIS®

Inclusion criteria

• Healthy adult, with vaccination history (by written evidence) of a minimum of 5 doses of a tetanus, diphtheria and poliomyelitis containing vaccine as recommended in the French vaccination calendar at 18 years old, and a maximum of 8 doses.
• Last dose of a tetanus and/or diphtheria and/or poliomyelitis containing vaccine administered either alone or in combination at least 5 years prior to the administration of the first study vaccine.

Exclusion criteria

• Prior known hypersensitivity reaction to any diphtheria and/or tetanus and/or poliomyelitis and/or pertussis containing vaccine
• Any current (≤ 3 days) significant underlying disease or acute febrile illness (oral temperature ≥37.5°C)
• Known immunological deficiency
• Known malignant disease
• Known neurological disorder
• Any long-term (≥ 14 days) non steroid anti-inflammatory therapy given daily within the previous 30 days
• Known history of severe thrombocytopenia or any coagulation disorder that would contraindicate intramuscular injection
• Any previous (≤ 90 days) administration of blood-derived products or immunoglobulins or scheduled to be administered through Visit 3
• Any recent administration (≤ 30 days) of a vaccine or scheduled vaccination