Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06178471

Safety, Feasibility and Clinical Utility of Critical Care Transesophageal Echocardiography in Hong Kong

Critical care echocardiography is increasingly recognized as an essential skill for intensivists to achieve during their training and fellowship. It serves to provide critical information to guide clinical management in patients with hemodynamic collapse and respiratory insufficiency. While transthoracic echocardiography (TTE) could be adequate for assessment in most situations, patient factors such as body habitus, presence of chest drains and tubes, presence of thoracic surgical dressings, requirement of high ventilatory support may impede operators from obtaining satisfactory images for evaluation. Moreover, operators in TTE require time and experience for adequate skill and technique acquisition. In specific pathologies such as infective endocarditis, presence of thrombus in left atrial appendage, and evaluation of intracardiac shunts, TEE has been shown to be superior to TTE for proper and accurate diagnosis. Therefore, TEE is widely accepted as the preferred and essential modality for echocardiographic examination especially in European countries. Countries such as France and North American have included critical care TEE as a core curriculum in the critical care training pathway.

In Hong Kong, only basic critical care echocardiography using TTE is required during training and in clinical practice. TEE evaluation is mostly performed in cardiac surgery units by cardiac anesthetists and in stable patients by cardiologists. Critical care TEE is seldom performed by intensivists independently for hemodynamic assessment and evaluation of cardiopulmonary failure. This study describes the safety, feasibility, and clinical utility of critical care TEE by critical care fellows in a university-affiliated institute providing tertiary care to the territory. With implementation of this essential technique in a single center, this study serves to act as a generalizable guidance to achieve an ultimate goal of incorporating this technique as core curriculum in critical care training in parts of the world where critical care TEE is not well established.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≧ 18; AND
  • Admitted to the mixed medical-surgical intensive care units of Queen Mary Hospital in Hong Kong; AND
  • Intubated for invasive mechanical ventilation; AND
  • Clinically indicated for transesophageal echocardiography (TEE)

Exclusion criteria

Patient possessing absolute contraindication(s) to TEE examination according to the ASE guideline 2013:

  • Perforated viscus
  • Esophageal stricture
  • Esophageal tumor
  • Esophageal perforation
  • Esophageal laceration
  • Esophageal diverticulum
  • Active upper gastrointestinal bleed

Treatment and study plan

Transesophageal Echocardiography

Diagnostic Test

The use of transesophageal echocardiography to diagnose cardiopulmonary failure in ICU patients with suboptimal or inadequate transthoracic echocardiography examinations.

Primary outcomes

  1. Complication of TEE use in the ICU

    Time frame: Within 1 week following the TEE examination

    TEE complications include esophageal perforation, upper gastrointestinal bleeding, loss of artificial airway, oral bleeding, dental injury, odynophagia, mortality

Study contacts

Contact information is provided by the study sponsor or research team.

Wincy Ng, MRCP

CONTACT

[email protected]

64806646

Sponsors and collaborators

Lead sponsor

Queen Mary Hospital, Hong Kong

Other

Registry information

Acronym: SAFE-TEE

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Dec 21, 2023
Registry last updated
Oct 17, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.