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NCT Number: NCT06852079

Safety & Efficacy of Qurs e Fishar in Mild to Moderate Hypertensive Patients in Pakistan

The herbal medicine Qurs-e-Fishar to treat mild to moderate High blood pressure or hypertension comprises of Rauwolfia serpentina. A product of Hamdard Laboratories (Waqf) Pakistan.

A Phase III Safety & Efficacy Open-label, Single-Arm, Interventional, Multicenter, Study in mild to moderate hypertensive, adults (30 to 60 years of age) prescribed with study product for 12 weeks (84 days).

Primary End Points:

1. Reduction in diastolic blood pressure less than 130 / 80 mmHg at the end of the study period (accepted by WHO) or if there was a fall of 20 / 10 mmHg or more in diastolic blood pressure as compared to baseline. 2. Type, frequency and severity of ADRs during the study period.

Secondary End Points:

1. Compliance of the prescribed study medication.

Recruiting

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Taj Medical Complex, Hamdard University Hospital

Karachi, Sindh, Pakistan

Location status: Recruiting

Location contact

Dr. Adil Faraz

PRINCIPAL_INVESTIGATOR

Zeenat Bukhari Study Coordinator

CONTACT

[email protected]

+923363725023

CONTACT

[email protected]

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ability to sign ICD
  • Participant(s) are willing and able to fulfill the requirements of the study protocol
  • Mild to moderate hypertensive
  • Mild hypertension range (140-159/90-99 mm Hg)
  • Moderate hypertension range (160-179/100-109 mm Hg)
  • Be between the age of 30 to 60 year

Exclusion criteria

  • Patients with recent history of following will be excluded:
  • Severe hypertension,
  • Congestive cardiac failure,
  • Left ventricular failure,
  • Myocardial ischemia,
  • Renal failure or
  • Cerebrovascular accidents

Treatment and study plan

Qurs e Fishar

Other

Qurs e Fishar is a herbal remedy for Hypertension

Primary outcomes

  1. Blood Pressure

    Time frame: 12 weeks

    Blood pressure (in mmHg) will be measure at baseline and again at first follow-up (4th week), than at second follow-up (at 8th week) the end of treatment (12th week).

Sponsors and collaborators

Lead sponsor

Abdul Bari

Other

Collaborators

  • Hamdard University

Registry information

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Feb 28, 2025
Registry last updated
Feb 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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