Safety and Efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine for Facial Augmentation in Asian Population

Inclusion criteria

• Subjects intent to undergo facial filler treatment for either volume loss or contouring
• Subjects requiring treatment in two to four of pre-defined areas in the face (upper cheeks, nasolabial folds, temples, nose and chin)
• Require 3-5 ml of investigational products to achieve a clinically meaningful improvement in appearance
• Facial appearance as Han Chinese
• Non-pregnant, non-breast feeding female
• Signed informed consent

Exclusion criteria

• Previous facial surgery (e.g. rhinoplasty) or permanent implant in the area to be treated.
• History of chronic sinusitis or rhinitis (only applicable for subjects injected in the nose).
• Subjects who needs to use heavy glasses during the study (only applicable for subjects injected in the nose).
• Previous tissue augmenting therapy or contouring with permanent filler or fat injection in the facial area.
• Previous treatment with Hyaluronic acid (HA) fillers or Restylane Skinboosters in the facial area within 12 months before treatment.
• Previous treatment with non-HA fillers such as CaHA (Calcium Hydroxylapatite) or PLLA (Poly L-Lactic Acid) within 24 months before treatment.
• Previous revitalization with neurotoxin in the facial area within six (6) months before treatment.
• Previous tissue revitalization treatment with laser or light, mesotherapy, chemical peeling or dermabrasion in the facial area within six (6) months before treatment.
• Any medical condition that, in the opinion of the investigator, would make the subject unsuitable for inclusion (e.g. a chronic, relapsing or hereditary disease that may interfere with the outcome of the study).