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OpenTrials
Completed

NCT Number: NCT00451152

Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma

The purpose of this study was to evaluate the safety and intraocular pressure (IOP)-lowering efficacy of anecortave acetate for treatment of elevated IOP in patients with open-angle glaucoma.

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Key information

Conditions

Open-angle Glaucoma Eye Diseases Glaucoma Glaucoma, Open-Angle Ocular Hypertension

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Texas

San Antonio, Texas, 78257, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of open-angle glaucoma;
  • Other protocol-defined inclusion criteria may apply.

Exclusion criteria

  • Pseudoexfoliation;
  • Pigment dispersion component;
  • Other protocol-defined exclusion criteria may apply.

Treatment and study plan

Anecortave Acetate Sterile Suspension, 30 mg/mL

Drug

Administered by anterior juxtascleral depot (AJD) in study eye, either 0.25 mL or 0.5 mL. One injection, 24 months.

Anecortave Acetate Vehicle

Other

Administered by anterior juxtascleral depot (AJD) in study eye, 0.5 mL. One injection, 24 months.

Primary outcomes

  1. Mean Intraocular Pressure (IOP)

    Time frame: 3 months

Secondary outcomes

  1. Percent Treatment Failures

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Official study title

A Study of the Safety and IOP-Lowering Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
Mar 23, 2007
Registry last updated
Nov 28, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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