Skip to main content
OpenTrials
Completed

NCT Number: NCT01116908

Safe Drinking Water For Households With Infants Born to HIV-Positive Mothers Pilot Study

The purpose of this study is to assess whether children under 2 years and other members of households in which HIV-positive mothers are providing replacement and complementary feeding would potentially benefit from the use of a filter designed to eliminate microbial pathogens from drinking water at the household level.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Diarrhea Blood-Borne Infections Communicable Diseases Genital Diseases HIV Infection HIV Infections Immune System Diseases Immunologic Deficiency Syndromes Infections Lentivirus Infections Pathological Conditions, Signs and Symptoms RNA Virus Infections Retroviridae Infections Sexually Transmitted Diseases Sexually Transmitted Diseases, Viral Signs and Symptoms Signs and Symptoms, Digestive Urogenital Diseases Virus Diseases

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Ngwerere Health Clinic and Kasisi Health Clinic

Lusaka, Chongwe District, Lusaka Province, Zambia

About this study

Contaminated drinking water is a leading cause of morbidity and mortality in low-income settings. Safe drinking water is of particular concern for HIV-positive mothers since many HIV-infected Zambian women choose replacement feeding and early cessation of breastfeeding of infants to minimize the risk of transmission of the virus. This study builds upon preliminary baseline research which determined that HIV-positive mothers would potentially benefit from an intervention that encourages HIV-positive mothers to treat their water at the household level.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Known HIV-status based on clinical testing
  • Have a child between 6-12 months at the initiation of the study
  • Within the catchment area of Kasisi or Ngwerere health clinics, Chongwe district, Lusaka

Exclusion criteria

  • Lived in the catchment area less than one year or planning to move

Treatment and study plan

LifeStraw Family

Device

LifeStraw Family is a household water treatment technology that will be implemented in the household to improve drinking water quality

Primary outcomes

  1. Use of LifeStraw Family for children under 2 and all household members

    Time frame: One year

    Use, acceptability, and longevity of LifeStraw Family will be assessed for replacement and complementary feeds for children under 2 and for drinking water for all members of the household

Secondary outcomes

  1. Microbiological performance of LifeStraw Family

    Time frame: One year

    Microbiological performance of LifeStraw Family, measured in terms of thermotolerant coliforms (TTC), a well-established WHO indicator organism for faecal contamination

  2. Impact of LifeStraw Family on longitudinal prevalence of diarrhea

    Time frame: One year

    Impact of the intervention on longitudinal prevalence of diarrhoea among infants under 2 years and all household members, measured both as reported by the primary caretaker of the child and by their weight-for-age z-score (WAZ) as a proxy for diarrhoea

Sponsors and collaborators

Lead sponsor

London School of Hygiene and Tropical Medicine

Other

Collaborators

  • University Teaching Hospital, Lusaka, Zambia
  • University of Zambia
  • Vestergaard Frandsen

Registry information

Official study title

Safe Drinking Water For Households With Infants Born to HIV-Positive Mothers in Zambia: Piloting a Household Water Treatment Intervention

Acronym: SWIM

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
May 5, 2010
Registry last updated
Aug 15, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.