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NCT Number: NCT01885299

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)

Recruiting

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Penrose Cancer Center, Colorado Springs, Colorado, United States

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About this study

The Registry is designed to help SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) users to understand utilization of and key treatment outcomes for these treatment approaches. Some of the objectives include:

Allow participants to record information about usage of SRS/SBRT in everyday practice, including patient characteristics and disease information, treatment plans and outcomes Provide participants with ready access to data for publication of their own experience and as a tool for establishing collaborations with other participating sites Facilitate quality improvement efforts for individual treatment providers Understand the effectiveness of different treatment plans for different types of lesions, diseases and treatments

The Registry tracks select outcomes for each condition treated by SRS/SBRT (for example, PSA for prostate cancer); the Registry also provides individual participants the ability to add additional outcomes for each and any condition of specific interest to their institutions.

The Registry is hosted by Vision Tree, Inc who is an independent vendor of electronic registries; they are responsible for HIPAA compliance, including all security mechanisms.

Patients will be enrolled prospectively. Some retrospective patient data is likely to be included in order to capture both short and longer term outcomes data.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of benign or malignant tumors or other conditions deemed treatable by stereotactic radiosurgery or stereotactic body radiotherapy
  • Willingness to sign an Informed Consent Document or verbally agree to participation

Exclusion criteria

  • There are no specific exclusion criteria, but patients who are unwilling to sign the ICD or who decline participation will not be included

Treatment and study plan

SRS/SBRT

Radiation

Intervention varies by condition being treated.

Primary outcomes

  1. Overall survival

    Time frame: Up to 5 years

    Survival from time of treatment to death

Secondary outcomes

  1. Local and distant recurrence

    Time frame: One to Five years

    Calculated from time of treatment to recurrence

Other outcomes

  1. Treatment toxicity

    Time frame: Immediate -5 years

    Complications of treatment. These complications are organ specific depending on which organ is being treated. For example, if the prostate is being treated,there may be rectal and urinary complications. If the brain is being treated, there may be headaches or nausea. The Radiation Therapy Oncology Group (RTOG) scale used for defining and measuring complications of radiotherapy is incorporated into the Registry database.

Study contacts

Contact information is provided by the study sponsor or research team.

Jan Jenkins, RN

CONTACT

[email protected]

Joanne Davis, PHD

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

The Radiosurgery Society

Other

Collaborators

  • VisionTree

Registry information

Official study title

Multi-Institution Registry of SRS/SBRT Procedures

Important dates

Study start
2012
Primary completion
2030
Study completion
2030
First posted
Jun 24, 2013
Registry last updated
Sep 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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