Fondation Ophtalmologique A de Rothschild
Paris, 75019, France
NCT Number: NCT02894411
The paralysis of the fourth cranial nerve (paralysis IV), commonly known as the superior oblique muscle (SO) paralysis, represents half of vertical strabismus. The diagnosis of SO paralysis and of its congenital or acquired etiology, are based on a range of clinical findings. The three main clinical diagnostic elements are the hypertropia in paralyzed side which increases in adducted position, the positivity of Bielschowsky head tilt test and the twisting of the eye fundus. These criteria are always considered together and are interdependent. The diagnostic value and the sensitivity of each of these signs is not defined. Brain and orbital Magnetic Resonance Imaging (MRI) allowed a better understanding of the physiopathology of a number of oculomotor disorders.
For this reason, MRI constitute a reference for the SO palsy. The atrophy of the SO muscle is qualitatively determined by the asymmetry of muscle volume on two contiguous coronal MRI.
The diagnostic value of various clinical signs observed in SO paralysis (sensitivity, specificity) remains unknown.
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Notify Me18 year and older
All sexes
Observational
Paris, 75019, France
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
For the subjects without oculomotor disorder
For the patients with SO muscle unilateral paralysis
Exclusion criteria
Time frame: baseline
The angle of objective ocular torsion is measured on a photography of the eye fundus.
Fondation Ophtalmologique Adolphe de Rothschild
Network
Acronym: EXCYCLOTORSION
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