Role of Patient Selection for Pancreatic Resections

Pancreatic surgery is complicated and risky, especially for pancreatic cancer. It's been noticed that having these surgeries done at specialized centers can lead to better outcomes and survival rates. However, factors like patient selection and hospital conditions also play an important role. Some studies show that more surgeries done at a hospital might not always mean better results, as the type of patients and procedures can vary. To understand this better, the present study compared outcomes and patient characteristics between high-volume pancreatic centers and others.

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Key information

Conditions

Pancreas Disease Digestive System Diseases Pancreatic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The study utilized German nationwide administrative data (diagnosis-related group statistics) spanning from 2010 to 2018. Persons who underwent pancreatic resections during this period were included, with exclusions for certain criteria like underage and type of procedure. Various factors including patient demographics, diagnoses, procedures, and comorbidities were analyzed to assess in-hospital mortality rates. High-volume pancreatic centers (HVPCs) were identified as those performing at least 50 procedures annually. Statistical analyses included comparing crude and adjusted mortality rates and assessing patient characteristics between HVPCs and non-HVPCs. Models were adjusted for multiple variables, and methods like the Cochran-Armitage trend test and mixed models were employed. Additionally, the study investigated how differences in patient characteristics between HVPCs and non-HVPCs affected mortality rates.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

partial or total pancreatic resections between 2010 and 2018

Exclusion criteria

childhood (<18 years)
subjects with a pancreatic transplantation procedure
missing information on age or gender

Treatment and study plan

Persons with pancreatic resection in a hospital with at least 50 pancreatic resections annually (observational),

Other

Persons that have undergone a pancreatic resection at a hospital with at least 50 pancreatic resections annually (observational)

Persons with pancreatic resection in a hospital not performing at least 50 pancreatic resections annually (observational),

Other

Persons that have undergone a pancreatic resection at a hospital with not at least 50 pancreatic resections annually (observational)

Primary outcomes

In-hospital mortality

Time frame: 30 days

Death

Sponsors and collaborators

Lead sponsor

Medizinische Hochschule Brandenburg Theodor Fontane

Other

Registry information

Official study title

Importance of Patient Characteristics in Identifying and Selecting Patients Suitable for Pancreatic Resection

Acronym: PatSelPanc

Important dates

Study start: 2010
Primary completion: 2018
Study completion: 2018
First posted: Apr 30, 2024
Registry last updated: Apr 30, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed