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NCT Number: NCT07510204

Role of MRI in Perianal Fistula

The aim of this study is to assess the diagnostic accuracy of MRI in detecting and assessment the primary fistulous tract, internal openings, secondary extensions, and associated abscesses. (and compare these findings with the surgical findings in patients who underwent surgery).

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Key information

Conditions

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag University Hospital

Sohag, Sohag Governorate, Egypt

Location contact

Merit Nabil Sobhy, Resident

CONTACT

[email protected]

01271935119

Merit Nabil Sobhy, Resident

PRINCIPAL_INVESTIGATOR

About this study

This study aims to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in the preoperative assessment of anal fistula. MRI has become an essential imaging modality for the evaluation of perianal fistulous disease due to its superior soft-tissue contrast and ability to delineate fistulous tracts, internal openings, secondary extensions, and associated abscesses.

Patients clinically suspected of having anal fistula and scheduled for surgical management will undergo preoperative MRI examination. The MRI protocol will include multiplanar T1-weighted and T2-weighted sequences, with or without fat suppression, to accurately identify the primary fistulous tract, internal opening, secondary ramifications, and any associated collections.

MRI findings will be recorded and classified according to standard fistula classification systems. These findings will then be compared with intraoperative surgical findings, which will be considered the reference standard.

The primary objective of this study is to determine the diagnostic accuracy of MRI in identifying the primary tract, internal opening, secondary extensions, and associated abscesses. Secondary objectives include assessing the role of MRI in preoperative planning and evaluating its ability to reduce recurrence rates through better delineation of fistulous anatomy.

The results of this study may contribute to improving preoperative evaluation strategies and optimizing surgical management in patients with perianal fistula.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients clinically diagnosed or suspected to have perianal fistula.
  • Both male and female patients of any age group
  • Patients referred for preoperative MRI assessment prior to surgical management.

Exclusion criteria

  • Patients with contraindications to MRI, such as pacemakers, metallic implants, or severe claustrophobia.
  • Patients refusing to participate in the study.

Treatment and study plan

Diagnostic imaging (MRI)

Other

MRI is performed as apart of peri-operative assessment of perianal fistula, This is not therapeutic intervention.

Primary outcomes

  1. Diagnostic accuracy of MRI in assessment of perianal fistula

    Time frame: Preoperative MRI assessment performed within 2 weeks before surgery.

    Evaluation of the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting and classifying perianal fistulas and associated complications. MRI findings will be compared with surgical findings as the reference standard to determine sensitivity, specificity, and overall diagnostic performance.

Study contacts

Contact information is provided by the study sponsor or research team.

Merit Nabil Sobhy, Resident

CONTACT

[email protected]

01271935119

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Role of Magnetic Resonance Imaging in Assessment of Perianal Fistula

Acronym: MRI PA fistula

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 3, 2026
Registry last updated
Apr 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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